What is the NOAEL for Guanine?
Guanine has 4 NOAEL studies in the database. The lowest reported value is 5Z93L87A1R UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Guanine
Also known as: EINECS 200-799-8, UNII-5Z93L87A1R, 2-Amino-1,9-dihydro-6H-purin-6-one, 2-Amino-1,9-dihydro-purin-6-one, 2-Amino-3,7-dihydro-6H-purin-6-one (+12 more)
CAS 73-40-5
Guanine (CAS 73-40-5) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
23 fields
Name
Guanine
CAS Number
73-40-5
DTXSID
DTXSID9052476
Molecular Formula
C5H5N5O
InChI Key
UYTPUPDQBNUYGX-UHFFFAOYSA-N
Monoisotopic Mass
151.04941
Synonyms
EINECS 200-799-8UNII-5Z93L87A1R2-Amino-1,9-dihydro-6H-purin-6-one2-Amino-1,9-dihydro-purin-6-one2-Amino-3,7-dihydro-6H-purin-6-one2-Amino-6-purinol2-Amino-Hypoxanthine2-amino-6,7-dihydro-3H-purin-6-one2-amino-6-oxopurine6-Hydroxy-2-aminopurineCI Natural white 1GUN
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
9 records
DyeOpacifer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care | European Commission | CosIng |
| pharmaceutical | FDA | United States Food and Drug Administration (FDA) |
| Personal care | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5Z93L87A1R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5Z93L87A1R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5Z93L87A1R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5Z93L87A1R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Guanine | 200-799-8 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Colorants
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GUANINE
ChEMBL Phase
3
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include Guanine?
Guanine appears on 4 regulatory/inventory lists including Europe; Personal care, pharmaceutical, Personal care, and 1 more. Source: EPA CPDat.
Is Guanine used in cosmetics?
Yes, Guanine is also indexed as a cosmetic ingredient under the name CI 75170 (Guanine). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Guanine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Guanine used outside industrial chemicals?
Guanine also appears in cosmetics, pharmaceutical databases.