NOAEL Data Cosmetic Ingredient

Hexadecyl(dimethyl)amine oxide

Also known as: N,N-Dimethylhexadecylamine N-oxide, Cetamine oxide, 1-Hexadecanamine, N,N-dimethyl-, N-oxide, EINECS 230-429-0, UNII-9DJ9RBA18Z

CAS 7128-91-8

Hexadecyl(dimethyl)amine oxide (CAS 7128-91-8) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for PALMITAMINE OXIDE →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 11 fields
Name
Hexadecyl(dimethyl)amine oxide
CAS Number
7128-91-8
DTXSID
DTXSID2051471
Molecular Formula
C18H39NO
InChI Key
IBOBFGGLRNWLIL-UHFFFAOYSA-N
Monoisotopic Mass
285.303165
Synonyms
N,N-Dimethylhexadecylamine N-oxideCetamine oxide1-Hexadecanamine, N,N-dimethyl-, N-oxideEINECS 230-429-0UNII-9DJ9RBA18Z

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 31 records
Surfactant (surface active agent)Solubility enhancerAnti-static agentCleaning agentSoftener and conditionerFoamantThickening agent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat
SCIL (9/2019)USEPASafer Chemical Ingredients List

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
9DJ9RBA18ZUNIIFDA UNII substance identifier--openFDA substances
9DJ9RBA18ZUNIIFDA UNII substance identifier--openFDA substances
9DJ9RBA18ZUNIIFDA UNII substance identifier--openFDA substances
9DJ9RBA18ZUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Surfactant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Hexadecyl(dimethyl)amine oxide?

Hexadecyl(dimethyl)amine oxide has 4 NOAEL studies in the database. The lowest reported value is 9DJ9RBA18Z UNII. Source: openFDA substances.

What regulatory lists include Hexadecyl(dimethyl)amine oxide?

Hexadecyl(dimethyl)amine oxide appears on 2 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, SCIL (9/2019). Source: EPA CPDat.

Is Hexadecyl(dimethyl)amine oxide used in cosmetics?

Yes, Hexadecyl(dimethyl)amine oxide is also indexed as a cosmetic ingredient under the name PALMITAMINE OXIDE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Hexadecyl(dimethyl)amine oxide come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Hexadecyl(dimethyl)amine oxide have different safety status in cosmetics vs industrial chemicals?

Hexadecyl(dimethyl)amine oxide is classified GHS Danger (H400, H410, H315, H318) in the chemicals database but is allowed in EU cosmetics.

Is Hexadecyl(dimethyl)amine oxide used outside industrial chemicals?

Hexadecyl(dimethyl)amine oxide also appears in cosmetics databases.