What is the NOAEL for Retinol, propanoate?
Retinol, propanoate has 4 NOAEL studies in the database. The lowest reported value is 32JK994WMC UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Retinol, propanoate
Also known as: EINECS 230-363-2, Propionic acid, retinol ester, Retinyl propionate
CAS 7069-42-3
Retinol, propanoate (CAS 7069-42-3) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Retinol, propanoate is classified GHS Danger (H360, H372, H413) in the chemicals database but is restricted in EU cosmetics at max 0.3% RE for leave-on and rinse-off face products; 0.05% RE for body lotions (Regulation EU 2024/996).
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Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
9 fields
Name
Retinol, propanoate
CAS Number
7069-42-3
DTXSID
DTXSID701019851
Molecular Formula
C23H34O2
InChI Key
SFRPDSKECHTFQA-ONOWFSFQSA-N
Monoisotopic Mass
342.25588
Synonyms
EINECS 230-363-2Propionic acid, retinol esterRetinyl propionate
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
3 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001.html |
| consumer_product | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001.html |
| Substances in Products - Canada (4/2014) | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001.html |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 32JK994WMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 32JK994WMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 32JK994WMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 32JK994WMC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
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ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Retinyl propionate | 230-363-2 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
restricted
Max
0.3% RE for leave-on and rinse-off face products; 0.05% RE for body lotions (Regulation EU 2024/996)
Category
active
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Retinol, propanoate?
Retinol, propanoate appears on 3 regulatory/inventory lists including Canada, consumer_product, Substances in Products - Canada (4/2014). Source: EPA CPDat.
Is Retinol, propanoate used in cosmetics?
Yes, Retinol, propanoate is also indexed as a cosmetic ingredient under the name Retinyl Propionate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Retinol, propanoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Retinol, propanoate have different safety status in cosmetics vs industrial chemicals?
Retinol, propanoate is classified GHS Danger (H360, H372, H413) in the chemicals database but is restricted in EU cosmetics at max 0.3% RE for leave-on and rinse-off face products; 0.05% RE for body lotions (Regulation EU 2024/996).
Is Retinol, propanoate used outside industrial chemicals?
Retinol, propanoate also appears in cosmetics, cannabis databases.