NOAEL Data REACH Registered Cosmetic Ingredient

Dihydrojasmone lactone

Also known as: gamma-Methyl-gamma-decanolactone, 2(3H)-Furanone, 5-hexyldihydro-5-methyl-, gamma-Methyl decalactone, BRN 0123344, EINECS 230-291-1 (+7 more)

CAS 7011-83-8

Dihydrojasmone lactone (CAS 7011-83-8) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for gamma-Methyldecalactone →

SOURCE noael studies public
NOAEL studies
9
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
Dihydrojasmone lactone
CAS Number
7011-83-8
DTXSID
DTXSID3041299
Molecular Formula
C11H20O2
InChI Key
ALWUKGXLBSQSMA-UHFFFAOYSA-N
Monoisotopic Mass
184.14633
Synonyms
gamma-Methyl-gamma-decanolactone2(3H)-Furanone, 5-hexyldihydro-5-methyl-gamma-Methyl decalactoneBRN 0123344EINECS 230-291-1FEMA No. 37865-Hexyldihydro-5-methyl-2(3H)-furanone4-Hydroxy-4-methyldecanoic acid gamma-lactonegamma-Methyldecalactone4-MethyldecanolideNSC 141822UNII-ANJ13KO1RK

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 9 of 9 studies
ValueUnitEndpointRouteSpeciesSource
ANJ13KO1RKUNIIFDA UNII substance identifier--openFDA substances
ANJ13KO1RKUNIIFDA UNII substance identifier--openFDA substances
ANJ13KO1RKUNIIFDA UNII substance identifier--openFDA substances
ANJ13KO1RKUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
1350ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
>5000mg/kg bwLD50oralRatNTP_ICE_acute_oral
-unitlessModel Score--NTP_ICE_endocrine
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 9 of 9 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered5-hexyldihydro-5-methylfuran-2(3H)-one230-291-1ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3182347
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Dihydrojasmone lactone?

Dihydrojasmone lactone has 9 NOAEL studies in the database. The lowest reported value is ANJ13KO1RK UNII. Source: openFDA substances.

What regulatory lists include Dihydrojasmone lactone?

Dihydrojasmone lactone appears on 4 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.

Is Dihydrojasmone lactone used in cosmetics?

Yes, Dihydrojasmone lactone is also indexed as a cosmetic ingredient under the name gamma-Methyldecalactone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Dihydrojasmone lactone come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Dihydrojasmone lactone used outside industrial chemicals?

Dihydrojasmone lactone also appears in cosmetics, pharmaceutical databases.