What is the NOAEL for Glutathione?
Glutathione has 5 NOAEL studies in the database. The lowest reported value is GAN16C9B8O UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Glutathione
Also known as: Glycine, L-.gamma.-glutamyl-L-cysteinyl-, Glycine, L-gamma-glutamyl-L-cysteinyl-, L-γ-Glutamyl-L-cysteinylglycine, Atomolan, GSH (+13 more)
CAS 70-18-8
Glutathione (CAS 70-18-8) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
Glutathione
CAS Number
70-18-8
DTXSID
DTXSID6023101
Molecular Formula
C10H17N3O6S
InChI Key
RWSXRVCMGQZWBV-WDSKDSINSA-N
Monoisotopic Mass
307.083806
Synonyms
Glycine, L-.gamma.-glutamyl-L-cysteinyl-Glycine, L-gamma-glutamyl-L-cysteinyl-L-γ-Glutamyl-L-cysteinylglycineAtomolanGSHHigh Thione Extract YH 15ReadiSorbGLUTATHIONE REDUCEDL-Glutathione reducedEINECS 200-725-4gamma-L-GlutamylcysteinylglycineGlutathione SH
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
Reducing agentFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| GAN16C9B8O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GAN16C9B8O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GAN16C9B8O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GAN16C9B8O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =100 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECOTOX |
Showing 5 of 5 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
0.1–2%
Category
antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GLUTATHIONE
ChEMBL Phase
3
Adverse Events
726
Bioactivity
5
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
2 records
FDA GRAS: At the notifier's request, FDA ceased to evaluate this notice
View full food safety profile →Frequently Asked Questions
What regulatory lists include Glutathione?
Glutathione appears on 2 regulatory/inventory lists including Canada; pharmaceutical, Canada; consumer_product; Substances in Products - Canada (4/2014). Source: EPA CPDat.
Is Glutathione used in cosmetics?
Yes, Glutathione is also indexed as a cosmetic ingredient under the name Glutathione. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Glutathione come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Glutathione used outside industrial chemicals?
Glutathione also appears in cosmetics, pharmaceutical, food safety databases.