What is the NOAEL for 3-Amino-2,6-dimethylphenol?
3-Amino-2,6-dimethylphenol has 40 NOAEL studies in the database. The lowest reported value is 150 mg/kg bw/day. Source: UnifiedCodex:SCCS_SHADOW:beta.noael_studies.
Also known as: EINECS 230-268-6, UNII-KK52J0MQ7D
CAS 6994-64-5
3-Amino-2,6-dimethylphenol (CAS 6994-64-5) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, SCCS.
View cosmetic safety profile for 3-Amino-2,6-Dimethylphenol →
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Europe; Personal care; restricted | European Commission | CosIng |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 150 | mg/kg bw/day | - | - | - | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 150 | mg/kg bw/day | - | - | - | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 150 | mg/kg bw/day | - | - | human | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| KK52J0MQ7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KK52J0MQ7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KK52J0MQ7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| KK52J0MQ7D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.08 | mg/kg bw | NOAEL | dermal | rat | SCCS_vision_codex |
| =0.08 | mg/kg bw | NOAEL | dermal | rat | SCCS_vision_codex |
| =0.08 | mg/kg bw | NOAEL | dermal | rat | SCCS_vision_codex |
| =0.08 | mg/kg bw | NOAEL | dermal | rat | SCCS_vision_codex |
| =60 | mg/kg bw/d | NOAEL | dermal | rat | SCCS_vision_codex |
| =60 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =60 | mg/kg bw/d | NOAEL | dermal | rat | SCCS_vision_codex |
| =60 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =60 | mg/kg bw/d | NOAEL | dermal | rat | SCCS_vision_codex |
| =60 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =60 | mg/kg bw/d | NOAEL | dermal | rat | SCCS_vision_codex |
| =60 | mg/kg bw/day | NOAEL | oral | rat | SCCS_vision_codex |
| =70 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =70 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =70 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =70 | mg/kg bw/day | NOAEL | - | rat | SCCS_vision_codex |
| =150 | mg/kg bw/day | NOAEL | - | - | SCCS_vision_codex |
| =150 | mg/kg bw/day | NOAEL | - | - | SCCS_vision_codex |
| =150 | mg/kg bw/day | NOAEL | - | - | SCCS_vision_codex |
| =150 | mg/kg bw/day | NOAEL | - | - | SCCS_vision_codex |
| =2000 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =2000 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =2000 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =2000 | mg/kg bw | NOAEL | oral | rat | SCCS_vision_codex |
| =0.08 | mg/kg bw | developmental toxicity | dermal | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| =60 | mg/kg bw/d | developmental toxicity | dermal | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| =60 | mg/kg bw/d | developmental toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 70 | mg/kg bw/day | genotoxicity | - | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 70 | mg/kg bw/day | genotoxicity | - | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 60 | mg/kg bw/day | reproductive toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 60 | mg/kg bw/day | reproductive toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 70 | mg/kg bw/day | reproductive toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
| 2000 | mg/kg bw | reproductive toxicity | oral | rat | UnifiedCodex:SCCS_SHADOW:beta.noael_studies |
Showing 40 of 40 studies
EU Scientific Committee opinions tied to the matched substance.
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCS/1529/14 | 18 June 2014 | safe | 2.0% | sensitisation potential not excluded |
Same-CAS cosmetic ingredient record for cross-vertical context.
3-Amino-2,6-dimethylphenol has 40 NOAEL studies in the database. The lowest reported value is 150 mg/kg bw/day. Source: UnifiedCodex:SCCS_SHADOW:beta.noael_studies.
3-Amino-2,6-dimethylphenol appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.
Yes, 3-Amino-2,6-dimethylphenol is also indexed as a cosmetic ingredient under the name 3-Amino-2,6-Dimethylphenol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
3-Amino-2,6-dimethylphenol also appears in cosmetics databases.