What is the NOAEL for Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated?
Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated has 68 NOAEL studies in the database. The lowest reported value is 287GF3Y3WC UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated
Also known as: Siloxanes and Silicones, di-Me, 3-hydroxypropyl Me, ethoxylated, Siloxanes, di-Me, 3-hydroxypropyl Me, oxirane-grafted, Siloxanes, di-Me, 3-hydroxypropyl Me, polymers with ethylene oxide, Silwet FZ 2171, Silwet L 7608 (+4 more)
CAS 68937-54-2
Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated (CAS 68937-54-2) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
68
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated
CAS Number
68937-54-2
DTXSID
DTXSID60894563
Synonyms
Siloxanes and Silicones, di-Me, 3-hydroxypropyl Me, ethoxylatedSiloxanes, di-Me, 3-hydroxypropyl Me, oxirane-graftedSiloxanes, di-Me, 3-hydroxypropyl Me, polymers with ethylene oxideSilwet FZ 2171Silwet L 7608Lambent MFF 159-100Silsurf D 212CGTransoft Hydro TF 405BDow Corning ES 5612 Formulation Aid
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
Lubricating agentEmulsifierFlow promoterWetting agent (non-aqueous)Hardener
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| active_ingredient; Pesticides | State of California | State of California |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 68 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 287GF3Y3WC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 287GF3Y3WC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 287GF3Y3WC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 287GF3Y3WC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 53D6AAS8X8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 53D6AAS8X8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 53D6AAS8X8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 53D6AAS8X8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 57JCH5967F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 57JCH5967F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 57JCH5967F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 57JCH5967F | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8PR7V1SVM0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8PR7V1SVM0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8PR7V1SVM0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8PR7V1SVM0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9OZ27X065D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9OZ27X065D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9OZ27X065D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9OZ27X065D | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A4M2DZJ8PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A4M2DZJ8PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A4M2DZJ8PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| A4M2DZJ8PU | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BD459BER8U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BD459BER8U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BD459BER8U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BD459BER8U | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BR768L8A3T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BR768L8A3T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BR768L8A3T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BR768L8A3T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G7DL1Y4G26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G7DL1Y4G26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G7DL1Y4G26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G7DL1Y4G26 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GIA7T764OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GIA7T764OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GIA7T764OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GIA7T764OD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q2H2M93YAH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q2H2M93YAH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q2H2M93YAH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q2H2M93YAH | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R8DD9LJ53A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R8DD9LJ53A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R8DD9LJ53A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R8DD9LJ53A | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SR8XVG49JV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SR8XVG49JV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 50 of 68 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
emulsifier
Frequently Asked Questions
What regulatory lists include Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated?
Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated appears on 3 regulatory/inventory lists including Indirect additives food contact (10/2018), active_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated used in cosmetics?
Yes, Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated is also indexed as a cosmetic ingredient under the name PEG-10 Dimethicone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated used outside industrial chemicals?
Polysiloxanes, di-Me, 3-hydroxypropyl Me, ethoxylated also appears in cosmetics databases.