NOAEL Data REACH Registered Cosmetic Ingredient

Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate

Also known as: Basic Yellow 87, Pyridinium, 1-methyl-4-[(methylphenylhydrazono)methyl]-, methyl sulfate, Pyridinium, 1-methyl-4-[(2-methyl-2-phenylhydrazinylidene)methyl]-, methyl sulfate (1:1), EINECS 269-503-2, UNII-224I63D8K4

CAS 68259-00-7

Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate (CAS 68259-00-7) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Basic Yellow 87 →

SOURCE noael studies public
NOAEL studies
28
SOURCE chemical inventory jurisdictions
Regulatory lists
5
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 11 fields
Name
Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate
CAS Number
68259-00-7
DTXSID
DTXSID9071349
Molecular Formula
C14H16N3.CH4O4S
InChI Key
LLLILZLFKGJCCV-UHFFFAOYSA-M
Monoisotopic Mass
338.117452
Synonyms
Basic Yellow 87Pyridinium, 1-methyl-4-[(methylphenylhydrazono)methyl]-, methyl sulfatePyridinium, 1-methyl-4-[(2-methyl-2-phenylhydrazinylidene)methyl]-, methyl sulfate (1:1)EINECS 269-503-2UNII-224I63D8K4

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 5 records
ListKeywordSource
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA
Europe; Personal care; restrictedEuropean CommissionCosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 28 of 28 studies
ValueUnitEndpointRouteSpeciesSource
224I63D8K4UNIIFDA UNII substance identifier--openFDA substances
224I63D8K4UNIIFDA UNII substance identifier--openFDA substances
224I63D8K4UNIIFDA UNII substance identifier--openFDA substances
224I63D8K4UNIIFDA UNII substance identifier--openFDA substances
50mg/kg bw/dayLOAELoralratCOSMOS_DB
10mg/kg bw/dayNOAELoralratCOSMOS_DB
=10mg/kg bw/dayNOAELdermalrabbitSCCNFP_vision_codex
=10mg/kg bw/dayNOAELdermalrabbitSCCNFP_vision_codex
=10mg/kg bw/dayNOAELdermalrabbitSCCNFP_vision_codex
=10mg/kg bw/dayNOAELdermalrabbitSCCNFP_vision_codex
=39mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
=39mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
=39mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
=39mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
=60mg/kg bwNOAEL-humanSCCNFP_vision_codex
=60mg/kg bwNOAEL-humanSCCNFP_vision_codex
=60mg/kg bwNOAEL-humanSCCNFP_vision_codex
=60mg/kg bwNOAEL-humanSCCNFP_vision_codex
=174mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
=174mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
=174mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
=174mg/kg bw/dayNOAELdermalguinea pigSCCNFP_vision_codex
60mg/kg bwdermal absorption-humanUnifiedCodex:SCCNFP:beta.noael_studies
10mg/kg bw/dayrepeated dose toxicitydermalrabbitUnifiedCodex:SCCNFP:beta.noael_studies
10mg/kg bw/dayrepeated dose toxicityoralrabbitUnifiedCodex:SCCNFP:beta.noael_studies
39mg/kg bw/dayrepeated dose toxicitydermalguinea pigUnifiedCodex:SCCNFP:beta.noael_studies
60mg/kg bwrepeated dose toxicityoralrabbitUnifiedCodex:SCCNFP:beta.noael_studies
174mg/kg bw/dayrepeated dose toxicitydermalguinea pigUnifiedCodex:SCCNFP:beta.noael_studies

Showing 28 of 28 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredMethyl 1-methyl-4-[(methylphenylhydrazono)methyl]pyridinium sulphate269-503-2ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate?

Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate has 28 NOAEL studies in the database. The lowest reported value is 224I63D8K4 UNII. Source: openFDA substances.

What regulatory lists include Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate?

Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate appears on 3 regulatory/inventory lists including children; Europe; Personal care, Europe; Personal care - hair coloring, Europe; Personal care; restricted. Source: EPA CPDat.

Is Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate used in cosmetics?

Yes, Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate is also indexed as a cosmetic ingredient under the name Basic Yellow 87. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate have different safety status in cosmetics vs industrial chemicals?

Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H400, H411).

Is Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate used outside industrial chemicals?

Methyl 1-methyl-4-((methylphenylhydrazono)methyl)pyridinium sulphate also appears in cosmetics databases.