What is the NOAEL for 4-Methyl-1-oxaspiro[5.5]undecene?
4-Methyl-1-oxaspiro[5.5]undecene has 4 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
4-Methyl-1-oxaspiro[5.5]undecene
Also known as: EINECS 269-401-8, 1-Oxaspiro(5.5)undec-4-ene, 4-methyl
CAS 68228-06-8
4-Methyl-1-oxaspiro[5.5]undecene (CAS 68228-06-8) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 4-Methyl-1-Oxaspiroundecene →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
4-Methyl-1-oxaspiro[5.5]undecene
CAS Number
68228-06-8
DTXSID
DTXSID6052403
Molecular Formula
C11H18O
InChI Key
WJHAXQNOQJKTQV-UHFFFAOYSA-N
Monoisotopic Mass
166.135765
Synonyms
EINECS 269-401-81-Oxaspiro(5.5)undec-4-ene, 4-methyl
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 837 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 1550 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 4-Methyl-1-oxaspiro[5.5]undecene?
4-Methyl-1-oxaspiro[5.5]undecene appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.
Is 4-Methyl-1-oxaspiro[5.5]undecene used in cosmetics?
Yes, 4-Methyl-1-oxaspiro[5.5]undecene is also indexed as a cosmetic ingredient under the name 4-Methyl-1-Oxaspiroundecene. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-Methyl-1-oxaspiro[5.5]undecene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-Methyl-1-oxaspiro[5.5]undecene used outside industrial chemicals?
4-Methyl-1-oxaspiro[5.5]undecene also appears in cosmetics databases.