What is the NOAEL for 3-Hexenal, (3Z)-?
3-Hexenal, (3Z)- has 11 NOAEL studies in the database. The lowest reported value is 6V54TKA96C UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
3-Hexenal, (3Z)-
Also known as: Cis-3-Hexenal
CAS 6789-80-6
3-Hexenal, (3Z)- (CAS 6789-80-6) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
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eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
7 fields
Name
3-Hexenal, (3Z)-
CAS Number
6789-80-6
DTXSID
DTXSID30884335
Molecular Formula
C6H10O
InChI Key
GXANMBISFKBPEX-ARJAWSKDSA-N
Monoisotopic Mass
98.073165
Synonyms
Cis-3-Hexenal
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 6V54TKA96C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6V54TKA96C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6V54TKA96C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6V54TKA96C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =1560 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =127 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =127 | mg/kg bw/day | NOAEL | oral: drinking water | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =127 | mg/kg bw/day | NOAEL | oral: drinking water | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
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EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
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Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 3-Hexenal, (3Z)-?
3-Hexenal, (3Z)- appears on 4 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), consumer_product, and 1 more. Source: EPA CPDat.
Is 3-Hexenal, (3Z)- used in cosmetics?
Yes, 3-Hexenal, (3Z)- is also indexed as a cosmetic ingredient under the name cis-3-Hexenal. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Hexenal, (3Z)- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Hexenal, (3Z)- used outside industrial chemicals?
3-Hexenal, (3Z)- also appears in cosmetics, food safety, cannabis databases.