What is the NOAEL for 4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one?
4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one has 7 NOAEL studies in the database. The lowest reported value is 67GL43KSFC UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one
Also known as: 3-Buten-2-one, 4-(2,4,6-trimethyl-3-cyclohexen-1-yl)-, 3-07-00-00646, BRN 3243121, EINECS 267-158-2, Iritone (+1 more)
CAS 67801-38-1
4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one (CAS 67801-38-1) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
NOAEL studies
NOAEL studies
7
SOURCE
Chemical inventory jurisdictions
Regulatory lists
1
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one
CAS Number
67801-38-1
DTXSID
DTXSID1052371
Molecular Formula
C13H20O
InChI Key
FETSKTIMHFKZNF-UHFFFAOYSA-N
Monoisotopic Mass
192.151415
Synonyms
3-Buten-2-one, 4-(2,4,6-trimethyl-3-cyclohexen-1-yl)-3-07-00-00646BRN 3243121EINECS 267-158-2Iritone4-(2,4,6-Trimethyl-4-cyclohexen-1-yl)-3-buten-2-one
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 67GL43KSFC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 67GL43KSFC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 67GL43KSFC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 67GL43KSFC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP ICE skin sensitization |
| 13500 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP ICE skin sensitization |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP ICE skin sensitization |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one?
4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one used in cosmetics?
Yes, 4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one is also indexed as a cosmetic ingredient under the name Iritone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one used outside industrial chemicals?
4-(2,4,6-Trimethyl-3-cyclohexen-1-yl)-3-buten-2-one also appears in cosmetics databases.