NOAEL Data Cosmetic Ingredient

2,2'-Methylenebis(4-aminophenol)

Also known as: UNII-433B39S481, 2,2'-Methylenebis 4-aminophenol, Bis-(5-amino-2-hydroxyphenyl)-methan

CAS 63969-46-0

2,2'-Methylenebis(4-aminophenol) (CAS 63969-46-0) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for 2,2'-METHYLENEBIS-4-AMINOPHENOL →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 9 fields
Name
2,2'-Methylenebis(4-aminophenol)
CAS Number
63969-46-0
DTXSID
DTXSID30213808
Molecular Formula
C13H14N2O2
InChI Key
HLIGKHFHQXRAOX-UHFFFAOYSA-N
Monoisotopic Mass
230.105528
Synonyms
UNII-433B39S4812,2'-Methylenebis 4-aminophenolBis-(5-amino-2-hydroxyphenyl)-methan

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records
Dye

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
433B39S481UNIIFDA UNII substance identifier--openFDA substances
433B39S481UNIIFDA UNII substance identifier--openFDA substances
433B39S481UNIIFDA UNII substance identifier--openFDA substances
433B39S481UNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Hair Dyes
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 2,2'-Methylenebis(4-aminophenol)?

2,2'-Methylenebis(4-aminophenol) has 4 NOAEL studies in the database. The lowest reported value is 433B39S481 UNII. Source: openFDA substances.

Is 2,2'-Methylenebis(4-aminophenol) used in cosmetics?

Yes, 2,2'-Methylenebis(4-aminophenol) is also indexed as a cosmetic ingredient under the name 2,2'-METHYLENEBIS-4-AMINOPHENOL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2,2'-Methylenebis(4-aminophenol) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 2,2'-Methylenebis(4-aminophenol) used outside industrial chemicals?

2,2'-Methylenebis(4-aminophenol) also appears in cosmetics databases.