What is the NOAEL for Sodium erythorbate?
Sodium erythorbate has 19 NOAEL studies in the database. The lowest reported value is 6 mg/kg bw/day in Consumers. Source: EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium erythorbate
Also known as: Sodium erythorbate (D-erythro-Hex-2-enonic acid, .gamma.-lactone, monosodium salt), Sodium erythorbate (1:1), D-erythro-Hex-2-enonic acid, gamma-lactone, sodium salt (1:1), D-Erythro-hex-2-enonic acid, gamma-lactone, monosodium salt, D-erythro-Hex-2-enonic acid, .gamma.-lactone, sodium salt (1:1) (+5 more)
CAS 6381-77-7
Sodium erythorbate (CAS 6381-77-7) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
19
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Sodium erythorbate
CAS Number
6381-77-7
DTXSID
DTXSID5020570
Molecular Formula
C6H8O6.Na
InChI Key
PPASLZSBLFJQEF-RKJRWTFHSA-M
Synonyms
Sodium erythorbate (D-erythro-Hex-2-enonic acid, .gamma.-lactone, monosodium salt)Sodium erythorbate (1:1)D-erythro-Hex-2-enonic acid, gamma-lactone, sodium salt (1:1)D-Erythro-hex-2-enonic acid, gamma-lactone, monosodium saltD-erythro-Hex-2-enonic acid, .gamma.-lactone, sodium salt (1:1)EINECS 228-973-9Hex-2-enonic acid gamma-lactone, D-erythro-, monosodium saltIsoascorbic acid sodium saltMonosodium D-erythro-hex-2-enonic acid gamma-lactoneUNII-BZ468R6XRD
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
12 records
AntioxidantChemical reaction regulatorBiocideProcessing aids not otherwise specifiedSurface modifierDyeFillerFood preservativeOxidizing agent
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| animal_products | USDA | United States Department of Agriculture (USDA) |
| fracking | FracFocus | FracFocus |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| fracking; water | NY Department of Conservation | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 19 of 19 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =6 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =6 | mg/kg bw/day | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =10.57 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| BZ468R6XRD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BZ468R6XRD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BZ468R6XRD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| BZ468R6XRD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =6.87 | % diet | LOEL | oral | Rat | ToxValDB_ECOTOX |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =650 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =650 | mg/kg bw/day | NOAEL | oral: drinking water | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 900 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =900 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 1030 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 2500 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 2968 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 3300 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 3435 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 12500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
Showing 19 of 19 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,3-didehydro-3-O-sodio-D-erythro-hexono-1,4-lactone | 228-973-9 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL2309028
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium erythorbate?
Sodium erythorbate appears on 5 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, animal_products, fracking, and 2 more. Source: EPA CPDat.
Is Sodium erythorbate used in cosmetics?
Yes, Sodium erythorbate is also indexed as a cosmetic ingredient under the name Sodium Erythorbate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium erythorbate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Sodium erythorbate used outside industrial chemicals?
Sodium erythorbate also appears in cosmetics, pharmaceutical, cannabis databases.