What is the NOAEL for Pramoxine hydrochloride?
Pramoxine hydrochloride has 4 NOAEL studies in the database. The lowest reported value is 88AYB867L5 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Pramoxine hydrochloride
Also known as: 4-(3-(p-Butoxyphenoxy)propyl)morpholine hydrochloride, p-Butoxyphenyl gamma-morpholinopropyl ether hydrochloride, EINECS 211-293-1, gamma-Morpholinopropyl 4-n-butoxyphenyl ether hydrochloride, NSC 25573 (+3 more)
CAS 637-58-1
Pramoxine hydrochloride (CAS 637-58-1) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
Pramoxine hydrochloride is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Pramoxine hydrochloride
CAS Number
637-58-1
DTXSID
DTXSID2047777
Molecular Formula
C17H27NO3.ClH
InChI Key
SYCBXBCPLUFJID-UHFFFAOYSA-N
Monoisotopic Mass
329.175771
Synonyms
4-(3-(p-Butoxyphenoxy)propyl)morpholine hydrochloridep-Butoxyphenyl gamma-morpholinopropyl ether hydrochlorideEINECS 211-293-1gamma-Morpholinopropyl 4-n-butoxyphenyl ether hydrochlorideNSC 25573Prax LotionPramoxine HClUNII-88AYB867L5
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Antioxidant
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 88AYB867L5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 88AYB867L5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 88AYB867L5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 88AYB867L5 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PRAMOXINE HYDROCHLORIDE
ChEMBL Phase
4
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
Is Pramoxine hydrochloride used in cosmetics?
Yes, Pramoxine hydrochloride is also indexed as a cosmetic ingredient under the name Pramoxine HCl. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Pramoxine hydrochloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Pramoxine hydrochloride have different safety status in cosmetics vs industrial chemicals?
Pramoxine hydrochloride is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H319, H335).
Is Pramoxine hydrochloride used outside industrial chemicals?
Pramoxine hydrochloride also appears in cosmetics, pharmaceutical databases.