What is the NOAEL for Brilliant Green?
Brilliant Green has 4 NOAEL studies in the database. The lowest reported value is G0L543D370 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Brilliant Green
Also known as: Ethanaminium, N-[4-[[4-(diethylamino)phenyl]phenylmethylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-, sulfate (1:1), C.I.Basic Green 1, Malachite Green G, Avon Green A-4379, Brilliant Green B.P. (+14 more)
CAS 633-03-4
Brilliant Green (CAS 633-03-4) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Brilliant Green is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H302, H314, H315, H317, H318, H319, H400).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Brilliant Green
CAS Number
633-03-4
DTXSID
DTXSID1048700
Molecular Formula
C27H33N2.H2O4S
InChI Key
NNBFNNNWANBMTI-UHFFFAOYSA-M
Monoisotopic Mass
483.231754
Synonyms
Ethanaminium, N-[4-[[4-(diethylamino)phenyl]phenylmethylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-, sulfate (1:1)C.I.Basic Green 1Malachite Green GAvon Green A-4379Brilliant Green B.P.Brilliant Tungstate Green Toner GT-288EINECS 211-190-1Emerald GreenN,N,N',N'-Tetraaethyl-monoaminofuchsoniumhydrogensulfatBrilliant-grunZelen brilantniZelen malachitova G
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| banned; Europe; Personal care | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| G0L543D370 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G0L543D370 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G0L543D370 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| G0L543D370 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | [4-[4-(diethylamino)benzhydrylene]cyclohexa-2,5-dien-1-ylidene]diethylammonium hydrogen sulphate | 211-190-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1790039
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
6
Frequently Asked Questions
What regulatory lists include Brilliant Green?
Brilliant Green appears on 3 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, Canada; Personal care; Substances in PCP - Canada (4/2014), banned; Europe; Personal care. Source: EPA CPDat.
Is Brilliant Green used in cosmetics?
Yes, Brilliant Green is also indexed as a cosmetic ingredient under the name Basic Green 1. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Brilliant Green come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Brilliant Green have different safety status in cosmetics vs industrial chemicals?
Brilliant Green is prohibited in EU cosmetics but has active industrial GHS classifications (H301, H302, H314, H315, H317, H318, H319, H400).
Is Brilliant Green used outside industrial chemicals?
Brilliant Green also appears in cosmetics, pharmaceutical databases.