NOAEL Data REACH Registered Cosmetic Ingredient

Ethyl hexadecanoate

Also known as: EINECS 211-064-6, FEMA No. 2451, UNII-IRD3M534ZM, Ethyl N-hexadecanoate, Ethyl cetylate (+7 more)

CAS 628-97-7

Ethyl hexadecanoate (CAS 628-97-7) is a chemical substance. Key regulatory status: REACH registered, 8 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Ethyl Palmitate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
8
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
Ethyl hexadecanoate
CAS Number
628-97-7
DTXSID
DTXSID2047511
Molecular Formula
C18H36O2
InChI Key
XIRNKXNNONJFQO-UHFFFAOYSA-N
Monoisotopic Mass
284.27153
Synonyms
EINECS 211-064-6FEMA No. 2451UNII-IRD3M534ZMEthyl N-hexadecanoateEthyl cetylateEthyl hexadecanoate (ethyl palmitate)EthylpalmitateFEMA 2451HEXADECANOIC ACID,ETHYL ESTER MFC18 H36 O2Palmitic acid ethyl esterPalmitic acid, ethyl ester (8CI)WE(2:0/16:0)

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 12 records
Softener and conditionerFragranceNo specific technical functionFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 8 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
detected; Europe; Personal care - body adhesiveDanish Environmental Protection AgencyDanish EPA
Australia; Food and drug - smoking-related productsNew Zealand ESRCPCat
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble
Cons electronics mech appliances and machinery; detected; EuropeDanish EPADanish EPA
Cleaning products and household care - air freshener; EuropeDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
IRD3M534ZMUNIIFDA UNII substance identifier--openFDA substances
IRD3M534ZMUNIIFDA UNII substance identifier--openFDA substances
IRD3M534ZMUNIIFDA UNII substance identifier--openFDA substances
IRD3M534ZMUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
RegisteredEthyl palmitate211-064-6ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3561042
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Ethyl hexadecanoate?

Ethyl hexadecanoate has 4 NOAEL studies in the database. The lowest reported value is IRD3M534ZM UNII. Source: openFDA substances.

What regulatory lists include Ethyl hexadecanoate?

Ethyl hexadecanoate appears on 8 regulatory/inventory lists including Europe, detected; Europe; Personal care - body adhesive, Australia; Food and drug - smoking-related products, and 5 more. Source: EPA CPDat.

Is Ethyl hexadecanoate used in cosmetics?

Yes, Ethyl hexadecanoate is also indexed as a cosmetic ingredient under the name Ethyl Palmitate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ethyl hexadecanoate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Ethyl hexadecanoate used outside industrial chemicals?

Ethyl hexadecanoate also appears in cosmetics, pharmaceutical, cannabis databases.