What is the NOAEL for 1-O-Methylglycerol?
1-O-Methylglycerol has 9 NOAEL studies in the database. The lowest reported value is 0 unitless via Ocular in Rabbit. Source: NTP_ICE_eye_irritation.
NOAEL Data
Cosmetic Ingredient
1-O-Methylglycerol
Also known as: 1,2-Propanediol, 3-methoxy-, BRN 1719407, EINECS 210-791-6, Glycerin-alpha-monomethyl ether, Glycerol 1-monomethyl ether (+2 more)
CAS 623-39-2
1-O-Methylglycerol (CAS 623-39-2) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
SOURCE
noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
1-O-Methylglycerol
CAS Number
623-39-2
DTXSID
DTXSID3049336
Molecular Formula
C4H10O3
InChI Key
PSJBSUHYCGQTHZ-UHFFFAOYSA-N
Monoisotopic Mass
106.062994
Synonyms
1,2-Propanediol, 3-methoxy-BRN 1719407EINECS 210-791-6Glycerin-alpha-monomethyl etherGlycerol 1-monomethyl ether3-Methoxy-1,2-propanediolNSC 6752
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| - | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 4 | unitless | EPA Classification | Ocular | Rabbit | NTP_ICE_eye_irritation |
| 4G03VY2NKP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4G03VY2NKP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4G03VY2NKP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4G03VY2NKP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.1 | %/sec | Intensity | Ocular | - | NTP_ICE_eye_irritation |
| >180 | s | Lag time | Ocular | - | NTP_ICE_eye_irritation |
| - | % | Plateau level | Ocular | - | NTP_ICE_eye_irritation |
Showing 9 of 9 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Solvent
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3187682
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
Is 1-O-Methylglycerol used in cosmetics?
Yes, 1-O-Methylglycerol is also indexed as a cosmetic ingredient under the name Glycerin Methyl Ether. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1-O-Methylglycerol come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 1-O-Methylglycerol used outside industrial chemicals?
1-O-Methylglycerol also appears in cosmetics, pharmaceutical databases.