What is the NOAEL for 1,7-Dimethylxanthine?
1,7-Dimethylxanthine has 4 NOAEL studies in the database. The lowest reported value is Q3565Y41V7 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
1,7-Dimethylxanthine
Also known as: 3,7-Dihydro-1,7-dimethyl-1H-purine-2,6-dione, 1H-Purine-2,6-dione, 3,7-dihydro-1,7-dimethyl- (9CI), Paraxanthine, 5-26-13-00554, BRN 0197907 (+7 more)
CAS 611-59-6
1,7-Dimethylxanthine (CAS 611-59-6) is a chemical substance. Key regulatory status: 11 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
11
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
1,7-Dimethylxanthine
CAS Number
611-59-6
DTXSID
DTXSID2052281
Molecular Formula
C7H8N4O2
InChI Key
QUNWUDVFRNGTCO-UHFFFAOYSA-N
Monoisotopic Mass
180.064726
Synonyms
3,7-Dihydro-1,7-dimethyl-1H-purine-2,6-dione1H-Purine-2,6-dione, 3,7-dihydro-1,7-dimethyl- (9CI)Paraxanthine5-26-13-00554BRN 0197907EINECS 210-271-9NSC 400018p-XanthineXanthine, 1,7-dimethyl-UNII-Q3565Y41V71,7-Dimethyl-Xanthine1,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
11 records
| List | Keyword | Source |
|---|---|---|
| detected; pharmaceutical; soil | USGS | United States Geological Survey (USGS) |
| detected; ground_water; MN Chemical Screening; pharmaceutical | USGS | State of Minnesota |
| detected; ground_water; MN Chemical Screening; pharmaceutical | USGS | State of Minnesota |
| detected; MN Chemical Screening; wastewater | Minnesota Pollution Control Agency | State of Minnesota |
| detected; MN Chemical Screening; surface_water | Minnesota Pollution Control Agency | State of Minnesota |
| detected; MN Chemical Screening; surface_water | Minnesota Pollution Control Agency | State of Minnesota |
| detected; MN Chemical Screening; wastewater | Minnesota Pollution Control Agency | State of Minnesota |
| detected; drinking_water | Illinois EPA | CPCat |
| detected; drinking_water | Illinois EPA | CPCat |
| detected; drinking_water; MN Chemical Screening | EPA & USGS | State of Minnesota |
| detected; MN Chemical Screening; surface_water | NPS & EPA | State of Minnesota |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| Q3565Y41V7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q3565Y41V7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q3565Y41V7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Q3565Y41V7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PARAXANTHINE
ChEMBL Phase
0.5
Adverse Events
0
Bioactivity
4
Frequently Asked Questions
What regulatory lists include 1,7-Dimethylxanthine?
1,7-Dimethylxanthine appears on 6 regulatory/inventory lists including detected; pharmaceutical; soil, detected; ground_water; MN Chemical Screening; pharmaceutical, detected; MN Chemical Screening; wastewater, and 3 more. Source: EPA CPDat.
Is 1,7-Dimethylxanthine used in cosmetics?
Yes, 1,7-Dimethylxanthine is also indexed as a cosmetic ingredient under the name PARAXANTHINE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,7-Dimethylxanthine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,7-Dimethylxanthine used outside industrial chemicals?
1,7-Dimethylxanthine also appears in cosmetics, pharmaceutical databases.