What is the NOAEL for Cyclic AMP?
Cyclic AMP has 4 NOAEL studies in the database. The lowest reported value is E0399OZS9N UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Cyclic AMP
Also known as: Adenosine cyclic 3',5'-monophosphate, 4-26-00-03618, Adenosine cyclic 3',5'-phosphate, BRN 0052645, EINECS 200-492-9 (+15 more)
CAS 60-92-4
Cyclic AMP (CAS 60-92-4) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
View cosmetic safety profile for ADENOSINE CYCLIC PHOSPHATE →
Cross-Vertical Regulatory Divergence
Cyclic AMP is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
Cyclic AMP
CAS Number
60-92-4
DTXSID
DTXSID8040436
Molecular Formula
C10H12N5O6P
InChI Key
IVOMOUWHDPKRLL-KQYNXXCUSA-N
Monoisotopic Mass
329.05252
Synonyms
Adenosine cyclic 3',5'-monophosphate4-26-00-03618Adenosine cyclic 3',5'-phosphateBRN 0052645EINECS 200-492-9UNII-E0399OZS9N(1R,6R,7R,8R)-8-(6-aminopurin-9-yl)-4-hydroxy-4-oxo-3,5,9-trioxa-4l5-phosphabicyclo[4.3.0]nonan-7-ol(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-1,3,5,2l5-furo[3,2-d][1,3,2l5]dioxaphosphinin-2-one3'5'-Cyclic AMP6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-D][1,3,2]dioxaphosphinine-2,7-diol 2-oxideAcrasinAdenosine 3',5'-cyclophosphate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| E0399OZS9N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E0399OZS9N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E0399OZS9N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E0399OZS9N | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CYCLIC ADENOSINE MONOPHOSPHATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Frequently Asked Questions
What regulatory lists include Cyclic AMP?
Cyclic AMP appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Canada; pharmaceutical. Source: EPA CPDat.
Is Cyclic AMP used in cosmetics?
Yes, Cyclic AMP is also indexed as a cosmetic ingredient under the name ADENOSINE CYCLIC PHOSPHATE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Cyclic AMP come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Cyclic AMP have different safety status in cosmetics vs industrial chemicals?
Cyclic AMP is classified GHS Danger (H314, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Cyclic AMP used outside industrial chemicals?
Cyclic AMP also appears in cosmetics, pharmaceutical databases.