What is the NOAEL for Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate?
Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate has 4 NOAEL studies in the database. The lowest reported value is 54M9O25201 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate
Also known as: Roxadimate
CAS 58882-17-0
Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate (CAS 58882-17-0) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Ethyl Dihydroxypropyl Aminobenzoate →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
7 fields
Name
Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate
CAS Number
58882-17-0
DTXSID
DTXSID70866716
Molecular Formula
C15H23NO4
InChI Key
CBZHHQOZZQEZNJ-UHFFFAOYSA-N
Monoisotopic Mass
281.162708
Synonyms
Roxadimate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
UV stabilizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 54M9O25201 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 54M9O25201 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 54M9O25201 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 54M9O25201 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ROXADIMATE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate?
Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate appears on 1 regulatory/inventory list including pharmaceutical. Source: EPA CPDat.
Is Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate used in cosmetics?
Yes, Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate is also indexed as a cosmetic ingredient under the name Ethyl Dihydroxypropyl Aminobenzoate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate used outside industrial chemicals?
Ethyl 4-[bis(2-hydroxypropyl)amino]benzoate also appears in cosmetics, pharmaceutical databases.