What is the NOAEL for Isoxazole, 5-methyl-?
Isoxazole, 5-methyl- has 4 NOAEL studies in the database. The lowest reported value is YC2P4IBF1E UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Isoxazole, 5-methyl-
Also known as: EINECS 227-289-8, NSC 52269
CAS 5765-44-6
Isoxazole, 5-methyl- (CAS 5765-44-6) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
View cosmetic safety profile for Alpha-Methyl-Alpha-Vinyl-Benzenepropanenitrile →
Cross-Vertical Regulatory Divergence
Isoxazole, 5-methyl- is prohibited in EU cosmetics but has active industrial GHS classifications (H226).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Isoxazole, 5-methyl-
CAS Number
5765-44-6
DTXSID
DTXSID4064000
Molecular Formula
C4H5NO
InChI Key
AGQOIYCTCOEHGR-UHFFFAOYSA-N
Monoisotopic Mass
83.037114
Synonyms
EINECS 227-289-8NSC 52269
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| YC2P4IBF1E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| YC2P4IBF1E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| YC2P4IBF1E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| YC2P4IBF1E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Frequently Asked Questions
Is Isoxazole, 5-methyl- used in cosmetics?
Yes, Isoxazole, 5-methyl- is also indexed as a cosmetic ingredient under the name Alpha-Methyl-Alpha-Vinyl-Benzenepropanenitrile. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Isoxazole, 5-methyl- come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Does Isoxazole, 5-methyl- have different safety status in cosmetics vs industrial chemicals?
Isoxazole, 5-methyl- is prohibited in EU cosmetics but has active industrial GHS classifications (H226).
Is Isoxazole, 5-methyl- used outside industrial chemicals?
Isoxazole, 5-methyl- also appears in cosmetics, food safety databases.