What is the NOAEL for 3-Benzylidenephthalide?
3-Benzylidenephthalide has 4 NOAEL studies in the database. The lowest reported value is N2S40871LM UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3-Benzylidenephthalide
Also known as: 3-Benzylidene-2-benzofuran-1(3H)-one, 1(3H)-Isobenzofuranone, 3-(phenylmethylene)-, Benzalphthalide, 3-(Phenylmethylene)-1(3H)-isobenzofuranone, 3-Benzalphthalide (+8 more)
CAS 575-61-1
3-Benzylidenephthalide (CAS 575-61-1) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
3-Benzylidenephthalide
CAS Number
575-61-1
DTXSID
DTXSID60870620
Molecular Formula
C15H10O2
InChI Key
YRTPZXMEBGTPLM-UHFFFAOYSA-N
Monoisotopic Mass
222.06808
Synonyms
3-Benzylidene-2-benzofuran-1(3H)-one1(3H)-Isobenzofuranone, 3-(phenylmethylene)-Benzalphthalide3-(Phenylmethylene)-1(3H)-isobenzofuranone3-BenzalphthalideBenzylidenephthalideEC 209-388-8Escalol 547NSC 2824UNII-N2S40871LMPhthalide, 3-benzylidene-AI3-17979
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
UV stabilizer
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| N2S40871LM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N2S40871LM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N2S40871LM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N2S40871LM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-benzylidenephthalide | 209-388-8 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
Is 3-Benzylidenephthalide used in cosmetics?
Yes, 3-Benzylidenephthalide is also indexed as a cosmetic ingredient under the name Benzalphthalide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Benzylidenephthalide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Benzylidenephthalide used outside industrial chemicals?
3-Benzylidenephthalide also appears in cosmetics databases.