What is the NOAEL for 4-Aminobutanoic acid?
4-Aminobutanoic acid has 4 NOAEL studies in the database. The lowest reported value is 2ACZ6IPC6I UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
4-Aminobutanoic acid
Also known as: 4-Aminobutyric acid, Butanoic acid, 4-amino-, Butyric acid, 4-amino-, gamma-Amino-n-butyric acid, gamma-Aminobutyric acid (+15 more)
CAS 56-12-2
4-Aminobutanoic acid (CAS 56-12-2) is a chemical substance. Key regulatory status: REACH registered, 15 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
View cosmetic safety profile for GABA (Gamma-Aminobutyric Acid) →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
15
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
4-Aminobutanoic acid
CAS Number
56-12-2
DTXSID
DTXSID6035106
Molecular Formula
C4H9NO2
InChI Key
BTCSSZJGUNDROE-UHFFFAOYSA-N
Monoisotopic Mass
103.063329
Synonyms
4-Aminobutyric acidButanoic acid, 4-amino-Butyric acid, 4-amino-gamma-Amino-n-butyric acidgamma-Aminobutyric acidEINECS 200-258-6GamastanGammageeGamulinEPA Pesticide Chemical Code 030802Acide amino-4- butyriqueUNII-2ACZ6IPC6I
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
Softener and conditionerNo specific technical functionFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
15 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| pharmaceutical | US International Trade Commission | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| active_ingredient; agricultural; applied; Pesticides | Arizona Department of Environmental Quality | State of Arizona |
| active_ingredient; agricultural; applied; fruits_and_vegetables; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; agricultural; Pesticides | USDA | United States Department of Agriculture (USDA) |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2ACZ6IPC6I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2ACZ6IPC6I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2ACZ6IPC6I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2ACZ6IPC6I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-aminobutyric acid | 200-258-6 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
20%
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GAMMA-AMINOBUTYRIC ACID
ChEMBL Phase
1
Adverse Events
60
Bioactivity
21
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
2 records
FDA GRAS: At the notifier's request, FDA ceased to evaluate this notice
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 4-Aminobutanoic acid?
4-Aminobutanoic acid appears on 8 regulatory/inventory lists including Europe, pharmaceutical, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 5 more. Source: EPA CPDat.
Is 4-Aminobutanoic acid used in cosmetics?
Yes, 4-Aminobutanoic acid is also indexed as a cosmetic ingredient under the name GABA (Gamma-Aminobutyric Acid). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 4-Aminobutanoic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 4-Aminobutanoic acid used outside industrial chemicals?
4-Aminobutanoic acid also appears in cosmetics, pharmaceutical, food safety, cannabis databases.