What is the NOAEL for Titanium(IV) n-butoxide?
Titanium(IV) n-butoxide has 5 NOAEL studies in the database. The lowest reported value is 127 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Titanium(IV) n-butoxide
Also known as: 1-Butanol titanium(4+) salt, Butyl titanate monomer, Butyl titanate(IV), (BuO)4Ti, EINECS 227-006-8, NSC 220232 (+7 more)
CAS 5593-70-4
Titanium(IV) n-butoxide (CAS 5593-70-4) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Titanium(IV) n-butoxide is classified GHS Danger (H226, H315, H318, H319, H335, H336, H227) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
18 fields
Name
Titanium(IV) n-butoxide
CAS Number
5593-70-4
DTXSID
DTXSID6041262
Molecular Formula
4C4H9O.Ti
InChI Key
YHWCPXVTRSHPNY-UHFFFAOYSA-N
Monoisotopic Mass
340.209302
Synonyms
1-Butanol titanium(4+) saltButyl titanate monomerButyl titanate(IV), (BuO)4TiEINECS 227-006-8NSC 220232NSC 59799Orgatics TA 25Orthotitanic acid, tetrabutyl esterTetrabutyltitanateTitanium butylateTyzor BPUNII-FJS8Q2MX9I
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
10 records
Film formerChemical reaction regulatorHardenerCatalystAdhesion/cohesion promoter
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =127 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| FJS8Q2MX9I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| FJS8Q2MX9I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| FJS8Q2MX9I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| FJS8Q2MX9I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Titanium tetrabutanolate | 227-006-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
What regulatory lists include Titanium(IV) n-butoxide?
Titanium(IV) n-butoxide appears on 1 regulatory/inventory list including Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Titanium(IV) n-butoxide used in cosmetics?
Yes, Titanium(IV) n-butoxide is also indexed as a cosmetic ingredient under the name Titanium Tetrabutoxide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Titanium(IV) n-butoxide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Titanium(IV) n-butoxide have different safety status in cosmetics vs industrial chemicals?
Titanium(IV) n-butoxide is classified GHS Danger (H226, H315, H318, H319, H335, H336, H227) in the chemicals database but is allowed in EU cosmetics.
Is Titanium(IV) n-butoxide used outside industrial chemicals?
Titanium(IV) n-butoxide also appears in cosmetics databases.