What is the NOAEL for Trans-2,cis-6-Nonadienal?
Trans-2,cis-6-Nonadienal has 8 NOAEL studies in the database. The lowest reported value is 93E895X03C UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Trans-2,cis-6-Nonadienal
Also known as: 2,6-Nonadienal, (2E,6Z)-, 2,6-Nonadienal, (E,Z)-, 2,6-Nonadienal, trans,cis-, (2E,6Z)-2,6-Nonadienal, (E,Z)-2,6-Nonadienal (+14 more)
CAS 557-48-2
Trans-2,cis-6-Nonadienal (CAS 557-48-2) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
Trans-2,cis-6-Nonadienal
CAS Number
557-48-2
DTXSID
DTXSID1047104
Molecular Formula
C9H14O
InChI Key
ZHHYXNZJDGDGPJ-MDAAKZFYSA-N
Monoisotopic Mass
138.104465
Synonyms
2,6-Nonadienal, (2E,6Z)-2,6-Nonadienal, (E,Z)-2,6-Nonadienal, trans,cis-(2E,6Z)-2,6-Nonadienal(E,Z)-2,6-Nonadienal(2E,6Z)-Nona-2,6-dienal(E,Z)-2,6-Nonadien-1-al4-01-00-03560BRN 1720980Cucumber aldehydeEINECS 209-178-6FEMA No. 3377
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
12 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 93E895X03C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 93E895X03C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 93E895X03C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 93E895X03C | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Trans-2,cis-6-Nonadienal?
Trans-2,cis-6-Nonadienal appears on 3 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe, IFRA Transparency. Source: EPA CPDat.
Is Trans-2,cis-6-Nonadienal used in cosmetics?
Yes, Trans-2,cis-6-Nonadienal is also indexed as a cosmetic ingredient under the name NONADIENAL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Trans-2,cis-6-Nonadienal come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Trans-2,cis-6-Nonadienal used outside industrial chemicals?
Trans-2,cis-6-Nonadienal also appears in cosmetics, food safety, cannabis databases.