What is the NOAEL for Phytosphingosine?
Phytosphingosine has 2 NOAEL studies in the database. The lowest reported value is GIN46U9Q2Q UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Phytosphingosine
Also known as: 4-D-Hydroxysphinganine, UNII-GIN46U9Q2Q, 4-R-hydroxyoctadecasphinganine
CAS 554-62-1
Phytosphingosine (CAS 554-62-1) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Phytosphingosine is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
2
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Phytosphingosine
CAS Number
554-62-1
DTXSID
DTXSID80203951
Molecular Formula
C18H39NO3
InChI Key
AERBNCYCJBRYDG-KSZLIROESA-N
Monoisotopic Mass
317.292994
Synonyms
4-D-HydroxysphinganineUNII-GIN46U9Q2Q4-R-hydroxyoctadecasphinganine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
15 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 2 of 2 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| GIN46U9Q2Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| GIN46U9Q2Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 2 of 2 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (2S,3S,4R)-2-aminooctadecane-1,3,4-triol | 439-210-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
PHYTOSPHINGOSINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include Phytosphingosine?
Phytosphingosine appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Phytosphingosine used in cosmetics?
Yes, Phytosphingosine is also indexed as a cosmetic ingredient under the name Phytosphingosine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Phytosphingosine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Phytosphingosine have different safety status in cosmetics vs industrial chemicals?
Phytosphingosine is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Is Phytosphingosine used outside industrial chemicals?
Phytosphingosine also appears in cosmetics, pharmaceutical databases.