NOAEL Data REACH Registered Cosmetic Ingredient

Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy-

Also known as: N,N'-Hexane-1,6-diylbis(12-hydroxyoctadecanamide), Hexamethylene bis-hydroxystearamide

CAS 55349-01-4

Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- (CAS 55349-01-4) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Hexamethylene Bis-hydroxystearamide →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy-
CAS Number
55349-01-4
DTXSID
DTXSID9052214
Molecular Formula
C42H84N2O4
InChI Key
CXPIOTOKMJNFSA-UHFFFAOYSA-N
Monoisotopic Mass
680.643109
Synonyms
N,N'-Hexane-1,6-diylbis(12-hydroxyoctadecanamide)Hexamethylene bis-hydroxystearamide

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 3 records
HumectantSoftener and conditioner

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
inert_ingredient; non_food_use; PesticidesEPACPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
=0.156mg/m3DNEL localinhalationHumanToxValDB_GESTIS_DNEL
=35.24mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
2FS31BFC0FUNIIFDA UNII substance identifier--openFDA substances
2FS31BFC0FUNIIFDA UNII substance identifier--openFDA substances
2FS31BFC0FUNIIFDA UNII substance identifier--openFDA substances
2FS31BFC0FUNIIFDA UNII substance identifier--openFDA substances

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered12-hydroxy-N-[6-(12-hydroxyoctadecanoylamino)hexyl]octadecanamide611-260-5ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy-?

Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- has 6 NOAEL studies in the database. The lowest reported value is 0.156 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.

What regulatory lists include Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy-?

Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.

Is Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- used in cosmetics?

Yes, Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- is also indexed as a cosmetic ingredient under the name Hexamethylene Bis-hydroxystearamide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- used outside industrial chemicals?

Octadecanamide, N,N'-1,6-hexanediylbis[12-hydroxy- also appears in cosmetics databases.