NOAEL Data Cosmetic Ingredient

P-Tolyl isovalerate

Also known as: Isovaleric Acid p-Tolyl Ester, Butanoic acid, 3-methyl-, 4-methylphenyl ester, p-Tolyl 3-methylbutyrate, Cresyl 3-methylbutanoate, p-, EINECS 259-465-5 (+7 more)

CAS 55066-56-3

P-Tolyl isovalerate (CAS 55066-56-3) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Ethyl Ricinoleate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields
Name
P-Tolyl isovalerate
CAS Number
55066-56-3
DTXSID
DTXSID6047159
Molecular Formula
C12H16O2
InChI Key
MVDPTWHTUYDLTL-UHFFFAOYSA-N
Monoisotopic Mass
192.11503
Synonyms
Isovaleric Acid p-Tolyl EsterButanoic acid, 3-methyl-, 4-methylphenyl esterp-Tolyl 3-methylbutyrateCresyl 3-methylbutanoate, p-EINECS 259-465-5FEMA No. 3387Methylphenyl 3-methylbutyrate, p-NSC 32511Tolyl isovalerate, P-Tolyl 3-methylbutyrate, p-UNII-C8JG0XTQ0Z4-Methylphenyl 3-methylbutanoate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
C8JG0XTQ0ZUNIIFDA UNII substance identifier--openFDA substances
C8JG0XTQ0ZUNIIFDA UNII substance identifier--openFDA substances
C8JG0XTQ0ZUNIIFDA UNII substance identifier--openFDA substances
C8JG0XTQ0ZUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3183410
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for P-Tolyl isovalerate?

P-Tolyl isovalerate has 4 NOAEL studies in the database. The lowest reported value is C8JG0XTQ0Z UNII. Source: openFDA substances.

What regulatory lists include P-Tolyl isovalerate?

P-Tolyl isovalerate appears on 4 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.

Is P-Tolyl isovalerate used in cosmetics?

Yes, P-Tolyl isovalerate is also indexed as a cosmetic ingredient under the name Ethyl Ricinoleate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for P-Tolyl isovalerate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is P-Tolyl isovalerate used outside industrial chemicals?

P-Tolyl isovalerate also appears in cosmetics, pharmaceutical, food safety, cannabis databases.