NOAEL Data Cosmetic Ingredient

Methyl 2-hydroxypropanoate

Also known as: Propanoic acid, 2-hydroxy-, methyl ester, EINECS 208-930-0, EINECS 218-449-8, 2-Hydroxypropanoic acid methyl ester, Methyl alpha-hydroxypropionate (+7 more)

CAS 547-64-8

Methyl 2-hydroxypropanoate (CAS 547-64-8) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Methyl Lactate →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields

Name

Methyl 2-hydroxypropanoate

CAS Number

547-64-8

DTXSID

DTXSID0027197

Molecular Formula

C4H8O3

InChI Key

LPEKGGXMPWTOCB-UHFFFAOYSA-N

Monoisotopic Mass

104.047344

Synonyms

Propanoic acid, 2-hydroxy-, methyl esterEINECS 208-930-0EINECS 218-449-82-Hydroxypropanoic acid methyl esterMethyl alpha-hydroxypropionateNSC 406248(+/-)-Methyl 2-hydroxypropanoate(+/-)-Methyl 2-hydroxypropionate(+/-)-Methyl lactateDL-Methyl lactatemethyl lactatemethyl 2-hydroxypropionate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records

SolventFlavouring and nutrientFragranceDeodorizer

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records

List	Keyword	Source
Cons electronics mech appliances and machinery; detected; Europe	Danish EPA	Danish EPA
Cons electronics mech appliances and machinery; detected; Europe	Danish EPA	Danish EPA
artificial_saliva; detected; emissions; Europe; Toys and children's products	Danish Environmental Protection Agency	Danish EPA
artificial_saliva; detected; emissions; Europe; Toys and children's products	Danish Environmental Protection Agency	Danish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 17 of 17 studies

Value	Unit	Endpoint	Route	Species	Source
H10S91526X	UNII	FDA UNII substance identifier	-	-	openFDA substances
H10S91526X	UNII	FDA UNII substance identifier	-	-	openFDA substances
H10S91526X	UNII	FDA UNII substance identifier	-	-	openFDA substances
H10S91526X	UNII	FDA UNII substance identifier	-	-	openFDA substances
>2000	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral
=75	mg/m3	LOAEL	-	Rat	INCHEM_WHO_kemi_kemi_ah1999_09
=75	mg/m3	LOAEL	-	Rat	INCHEM_WHO_kemi_kemi_ah1999_09
=75	mg/m3	LOAEL	-	Rat	INCHEM_WHO_kemi_kemi_ah1999_09
=75	mg/m3	LOAEL	-	Rat	INCHEM_WHO_kemi_kemi_ah1999_09
=0.5	mg/kg bw	NOAEL	oral	-	INCHEM_WHO_kemi_kemi_ah1999_09
=0.5	mg/kg bw	NOAEL	oral	-	INCHEM_WHO_kemi_kemi_ah1999_09
=0.5	mg/kg bw	NOAEL	oral	-	INCHEM_WHO_kemi_kemi_ah1999_09
=0.5	mg/kg bw	NOAEL	oral	-	INCHEM_WHO_kemi_kemi_ah1999_09
=200	mg/m3	NOAEL	inhalation	-	INCHEM_WHO_kemi_kemi_ah1999_09
=200	mg/m3	NOAEL	inhalation	-	INCHEM_WHO_kemi_kemi_ah1999_09
=200	mg/m3	NOAEL	inhalation	-	INCHEM_WHO_kemi_kemi_ah1999_09
=200	mg/m3	NOAEL	inhalation	-	INCHEM_WHO_kemi_kemi_ah1999_09

Showing 17 of 17 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL3183351

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Methyl 2-hydroxypropanoate?

Methyl 2-hydroxypropanoate has 17 NOAEL studies in the database. The lowest reported value is H10S91526X UNII. Source: openFDA substances.

What regulatory lists include Methyl 2-hydroxypropanoate?

Methyl 2-hydroxypropanoate appears on 2 regulatory/inventory lists including Cons electronics mech appliances and machinery; detected; Europe, artificial_saliva; detected; emissions; Europe; Toys and children's products. Source: EPA CPDat.

Is Methyl 2-hydroxypropanoate used in cosmetics?

Yes, Methyl 2-hydroxypropanoate is also indexed as a cosmetic ingredient under the name Methyl Lactate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Methyl 2-hydroxypropanoate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Methyl 2-hydroxypropanoate used outside industrial chemicals?

Methyl 2-hydroxypropanoate also appears in cosmetics, pharmaceutical databases.