What is the NOAEL for 3-Ethylhexahydro-2(3H)-benzofuranone?
3-Ethylhexahydro-2(3H)-benzofuranone has 3 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
Cosmetic Ingredient
3-Ethylhexahydro-2(3H)-benzofuranone
Also known as: 3-Ethylhexahydro-3H-benzofuran-2-one, 3-Ethylhexahydro-1-benzofuran-2(3H)-one, 2(3H)-Benzofuranone, 3-ethylhexahydro-, 3-Ethyloctahydrobenzofuran-2-one, Tonka lactone (+5 more)
CAS 54491-17-7
3-Ethylhexahydro-2(3H)-benzofuranone (CAS 54491-17-7) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for 3-Ethylhexahydro-3H-Benzofuran-2-One →
SOURCE
noael studies public
NOAEL studies
3
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
3-Ethylhexahydro-2(3H)-benzofuranone
CAS Number
54491-17-7
DTXSID
DTXSID0052203
Molecular Formula
C10H16O2
InChI Key
WUEULGLRESFOFL-UHFFFAOYSA-N
Monoisotopic Mass
168.11503
Synonyms
3-Ethylhexahydro-3H-benzofuran-2-one3-Ethylhexahydro-1-benzofuran-2(3H)-one2(3H)-Benzofuranone, 3-ethylhexahydro-3-Ethyloctahydrobenzofuran-2-oneTonka lactone3-ethylhexahydro-3H-benzofuranne-2-one3-Ethylhexahydro-3H-benzofuran-2-on3-etilhexahidro-3H-benzofuran-2-onaBENZOFURAN-2-ONE(3H), 3-ETHYLHEXAHYDRO-EINECS 259-185-3
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 3 of 3 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 969 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 4 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 3 of 3 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 3-Ethylhexahydro-2(3H)-benzofuranone?
3-Ethylhexahydro-2(3H)-benzofuranone appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.
Is 3-Ethylhexahydro-2(3H)-benzofuranone used in cosmetics?
Yes, 3-Ethylhexahydro-2(3H)-benzofuranone is also indexed as a cosmetic ingredient under the name 3-Ethylhexahydro-3H-Benzofuran-2-One. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Ethylhexahydro-2(3H)-benzofuranone come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Ethylhexahydro-2(3H)-benzofuranone used outside industrial chemicals?
3-Ethylhexahydro-2(3H)-benzofuranone also appears in cosmetics databases.