What is the NOAEL for Benzyl acetoacetate?
Benzyl acetoacetate has 4 NOAEL studies in the database. The lowest reported value is F9S0XGV18X UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Benzyl acetoacetate
Also known as: Butanoic acid, 3-oxo-, phenylmethyl ester, Acetoacetic acid, benzyl ester, Benzyl acetylacetate, Benzyl beta-ketobutyrate, Benzyl 3-oxobutanoate (+5 more)
CAS 5396-89-4
Benzyl acetoacetate (CAS 5396-89-4) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Benzyl acetoacetate is prohibited in EU cosmetics but has active industrial GHS classifications (H412).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
16 fields
Name
Benzyl acetoacetate
CAS Number
5396-89-4
DTXSID
DTXSID8063834
Molecular Formula
C11H12O3
InChI Key
WOFAGNLBCJWEOE-UHFFFAOYSA-N
Monoisotopic Mass
192.078644
Synonyms
Butanoic acid, 3-oxo-, phenylmethyl esterAcetoacetic acid, benzyl esterBenzyl acetylacetateBenzyl beta-ketobutyrateBenzyl 3-oxobutanoateEINECS 226-416-4FEMA No. 2136NSC 4391Phenylmethyl 3-oxobutanoateUNII-F9S0XGV18X
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
4 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| F9S0XGV18X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F9S0XGV18X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F9S0XGV18X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| F9S0XGV18X | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Benzyl acetoacetate | 226-416-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Benzyl acetoacetate?
Benzyl acetoacetate appears on 2 regulatory/inventory lists including Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is Benzyl acetoacetate used in cosmetics?
Yes, Benzyl acetoacetate is also indexed as a cosmetic ingredient under the name Benzyl Acetoacetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Benzyl acetoacetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Benzyl acetoacetate have different safety status in cosmetics vs industrial chemicals?
Benzyl acetoacetate is prohibited in EU cosmetics but has active industrial GHS classifications (H412).
Is Benzyl acetoacetate used outside industrial chemicals?
Benzyl acetoacetate also appears in cosmetics, cannabis databases.