What is the NOAEL for C.I. Basic Orange 2?
C.I. Basic Orange 2 has 7 NOAEL studies in the database. The lowest reported value is 2431787HMZ UNII. Source: openFDA substances.
NOAEL Data
IARC Group 3
Cosmetic Ingredient
C.I. Basic Orange 2
Also known as: Chrysoidine G, C.I. 11270, C.I. Basic Orange 2, monohydrochloride, Astra Chrysoidine R, Basic Orange 2 (+15 more)
CAS 532-82-1
C.I. Basic Orange 2 (CAS 532-82-1) is a chemical substance; key hazard signal: IARC Group 3. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, IARC.
SOURCE
NOAEL studies
NOAEL studies
7
SOURCE
Chemical inventory jurisdictions
Regulatory lists
1
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
26 fields
Name
C.I. Basic Orange 2
CAS Number
532-82-1
DTXSID
DTXSID0024559
Molecular Formula
C12H12N4.ClH
InChI Key
MCTQNEBFZMBRSQ-UHFFFAOYSA-N
Monoisotopic Mass
248.082874
Synonyms
Chrysoidine GC.I. 11270C.I. Basic Orange 2, monohydrochlorideAstra Chrysoidine RBasic Orange 2Brasilazina Orange YBrilliant Oil Orange Y BaseCalcozine Chrysoidine YCalcozine Orange YSChrysoidinChrysoidin YChrysoidin FB
IARC Carcinogen Classification
Carcinogenic hazard classification from IARC monograph evaluations.
SOURCE
IARC Monographs on the Identification of Carcinogenic Hazards to Humans
1 records
| Group | Meaning | Evaluated | Volume |
|---|---|---|---|
| Group 3 | Not classifiable | 1987 | 8, Sup 7 |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| - | Mutation Research/Reviews in Genetic Toxicology | Published Articles |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 2431787HMZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2431787HMZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2431787HMZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2431787HMZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3 | IARC group | IARC carcinogenicity classification | - | - | IARC Monographs |
| 3 | unitless | IARC group | - | - | NTP ICE cancer |
| =6670 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
Showing 7 of 7 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHRYSOIDINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include C.I. Basic Orange 2?
C.I. Basic Orange 2 appears on 0 regulatory/inventory lists including . Source: EPA CPDat.
Is C.I. Basic Orange 2 a carcinogen according to IARC?
C.I. Basic Orange 2 is classified by IARC as Group 3 — not classifiable as to its carcinogenicity to humans (evaluated 1987). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.
Is C.I. Basic Orange 2 used in cosmetics?
Yes, C.I. Basic Orange 2 is also indexed as a cosmetic ingredient under the name Basic Orange 2. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for C.I. Basic Orange 2 come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is C.I. Basic Orange 2 used outside industrial chemicals?
C.I. Basic Orange 2 also appears in cosmetics, pharmaceutical databases.