What is the NOAEL for Benzimidazole?
Benzimidazole has 6 NOAEL studies in the database. The lowest reported value is 2.61 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Benzimidazole
Also known as: 5-23-06-00196, BRN 0109682, EINECS 200-081-4, UNII-E24GX49LD8, BZI
CAS 51-17-2
Benzimidazole (CAS 51-17-2) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
Cross-Vertical Regulatory Divergence
Benzimidazole is prohibited in EU cosmetics but has active industrial GHS classifications (H302).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Benzimidazole
CAS Number
51-17-2
DTXSID
DTXSID8024573
Molecular Formula
C7H6N2
InChI Key
HYZJCKYKOHLVJF-UHFFFAOYSA-N
Monoisotopic Mass
118.053098
Synonyms
5-23-06-00196BRN 0109682EINECS 200-081-4UNII-E24GX49LD8BZI
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
PigmentDyeNo specific technical function
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =2.61 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =19.7 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| E24GX49LD8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E24GX49LD8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E24GX49LD8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| E24GX49LD8 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Benzimidazole | 200-081-4 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
BENZIMIDAZOLE
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
What regulatory lists include Benzimidazole?
Benzimidazole appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Benzimidazole used in cosmetics?
Yes, Benzimidazole is also indexed as a cosmetic ingredient under the name Benzimidazole. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Benzimidazole come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Benzimidazole have different safety status in cosmetics vs industrial chemicals?
Benzimidazole is prohibited in EU cosmetics but has active industrial GHS classifications (H302).
Is Benzimidazole used outside industrial chemicals?
Benzimidazole also appears in cosmetics, pharmaceutical databases.