What is the NOAEL for Citronellic acid?
Citronellic acid has 11 NOAEL studies in the database. The lowest reported value is 1JJT408R87 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Citronellic acid
Also known as: 6-Octenoic acid, 3,7-dimethyl-, 4-02-00-01610, BRN 1722960, 3,7-Dimethyl-6-octenoic acid, EINECS 207-939-7 (+3 more)
CAS 502-47-6
Citronellic acid (CAS 502-47-6) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Citronellic acid is classified GHS Danger (H311) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
11
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Citronellic acid
CAS Number
502-47-6
DTXSID
DTXSID1047106
Molecular Formula
C10H18O2
InChI Key
GJWSUKYXUMVMGX-UHFFFAOYSA-N
Monoisotopic Mass
170.13068
Synonyms
6-Octenoic acid, 3,7-dimethyl-4-02-00-01610BRN 17229603,7-Dimethyl-6-octenoic acidEINECS 207-939-7FEMA No. 3142UNII-1JJT408R87Citronellate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
6 records
BiocideDeodorizerFlavouring and nutrientFragranceAnti-dandruff
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe | European Commission | Fl@vis |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 11 of 11 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 1JJT408R87 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1JJT408R87 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1JJT408R87 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1JJT408R87 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =2610 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =50 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_EFSA |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =50 | mg/kg bw/day | NOEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 11 of 11 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CITRONELLIC ACID
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Citronellic acid?
Citronellic acid appears on 3 regulatory/inventory lists including IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Europe. Source: EPA CPDat.
Is Citronellic acid used in cosmetics?
Yes, Citronellic acid is also indexed as a cosmetic ingredient under the name Citronellic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Citronellic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Citronellic acid have different safety status in cosmetics vs industrial chemicals?
Citronellic acid is classified GHS Danger (H311) in the chemicals database but is allowed in EU cosmetics.
Is Citronellic acid used outside industrial chemicals?
Citronellic acid also appears in cosmetics, pharmaceutical, food safety, cannabis databases.