What is the NOAEL for Glycyl-histidyl-lysine?
Glycyl-histidyl-lysine has 4 NOAEL studies in the database. The lowest reported value is 39TG2H631E UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Glycyl-histidyl-lysine
Also known as: Kollaren, Gly-his-lys, NSC 379527, UNII-39TG2H631E, Growth-modulating peptide (human) (+4 more)
CAS 49557-75-7
Glycyl-histidyl-lysine (CAS 49557-75-7) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB.
View cosmetic safety profile for Copper Peptide (GHK-Cu, Copper Tripeptide-1) →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Glycyl-histidyl-lysine
CAS Number
49557-75-7
DTXSID
DTXSID30197831
Molecular Formula
C14H24N6O4
InChI Key
MVORZMQFXBLMHM-QWRGUYRKSA-N
Monoisotopic Mass
340.185903
Synonyms
KollarenGly-his-lysNSC 379527UNII-39TG2H631EGrowth-modulating peptide (human)Gly-L-His-L-Lysglycylhistidyllysineliver cell growth factorGHK Tripeptide
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 39TG2H631E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 39TG2H631E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 39TG2H631E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 39TG2H631E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1814493
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
Is Glycyl-histidyl-lysine used in cosmetics?
Yes, Glycyl-histidyl-lysine is also indexed as a cosmetic ingredient under the name Copper Peptide (GHK-Cu, Copper Tripeptide-1). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Glycyl-histidyl-lysine come from?
Safety data is sourced from EPA ToxValDB, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Glycyl-histidyl-lysine used outside industrial chemicals?
Glycyl-histidyl-lysine also appears in cosmetics, pharmaceutical databases.