NOAEL Data Cosmetic Ingredient

Bergenin

Also known as: UNII-L84RBE4IDC, (2R,3S,4S,4aR,10bS)-3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2H)-one, Cuscutin

CAS 477-90-7

Bergenin (CAS 477-90-7) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Bergenin →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 9 fields
Name
Bergenin
CAS Number
477-90-7
DTXSID
DTXSID4048141
Molecular Formula
C14H16O9
InChI Key
YWJXCIXBAKGUKZ-HJJNZUOJSA-N
Monoisotopic Mass
328.079432
Synonyms
UNII-L84RBE4IDC(2R,3S,4S,4aR,10bS)-3,4,8,10-Tetrahydroxy-2-(hydroxymethyl)-9-methoxy-3,4,4a,10b-tetrahydropyrano[3,2-c]isochromen-6(2H)-oneCuscutin

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Softener and conditioner

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
L84RBE4IDCUNIIFDA UNII substance identifier--openFDA substances
L84RBE4IDCUNIIFDA UNII substance identifier--openFDA substances
L84RBE4IDCUNIIFDA UNII substance identifier--openFDA substances
L84RBE4IDCUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL BERGENIN
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
3
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Bergenin?

Bergenin has 4 NOAEL studies in the database. The lowest reported value is L84RBE4IDC UNII. Source: openFDA substances.

Is Bergenin used in cosmetics?

Yes, Bergenin is also indexed as a cosmetic ingredient under the name Bergenin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Bergenin come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Bergenin used outside industrial chemicals?

Bergenin also appears in cosmetics, pharmaceutical databases.