NOAEL Data Cosmetic Ingredient

3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate)

Also known as: Butyric acid, 2-methyl-, 9-ester with 9,10-dihydro-9,10-dihydroxy-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-2-one-acetate, Visnadine

CAS 477-32-7

3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) (CAS 477-32-7) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Visnadine →

SOURCE NOAEL studies

NOAEL studies

SOURCE Chemical inventory jurisdictions

Regulatory lists

SOURCE EU CLP Annex VI

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields

Name

3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate)

CAS Number

477-32-7

DTXSID

DTXSID301023583

Molecular Formula

C21H24O7

InChI Key

GVBNSPFBYXGREE-CXWAGAITSA-N

Monoisotopic Mass

388.152203

Synonyms

Butyric acid, 2-methyl-, 9-ester with 9,10-dihydro-9,10-dihydroxy-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-2-one-acetateVisnadine

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records

Softener and conditioner

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records

List	Keyword	Source
pharmaceutical	US International Trade Commission	CPCat
Canada; pharmaceutical	DrugBank	DrugBank
Canada; pharmaceutical	DrugBank	DrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 5 of 5 studies

Value	Unit	Endpoint	Route	Species	Source
0RL4V0K263	UNII	FDA UNII substance identifier	-	-	openFDA substances
0RL4V0K263	UNII	FDA UNII substance identifier	-	-	openFDA substances
0RL4V0K263	UNII	FDA UNII substance identifier	-	-	openFDA substances
0RL4V0K263	UNII	FDA UNII substance identifier	-	-	openFDA substances
=1213	mg/kg bw	LD50	oral	Rat	NTP ICE acute oral

Showing 5 of 5 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed VISNADINE

ChEMBL Phase

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for 3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate)?

3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) has 5 NOAEL studies in the database. The lowest reported value is 0RL4V0K263 UNII. Source: openFDA substances.

What regulatory lists include 3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate)?

3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.

Is 3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) used in cosmetics?

Yes, 3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) is also indexed as a cosmetic ingredient under the name Visnadine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is 3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) used outside industrial chemicals?

3,4,5-Trihydroxy-2,2-dimethyl-6-chromanacrylic acid delta-lactone 4-acetate 3-(2-methylbutyrate) also appears in cosmetics, pharmaceutical databases.