What is the NOAEL for D-Glaucine?
D-Glaucine has 4 NOAEL studies in the database. The lowest reported value is NU19306XA7 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
D-Glaucine
Also known as: Boldine dimethyl ether, Bromcholitin, EINECS 207-501-5, S-(+)-Glaucine, Glauvent (+5 more)
CAS 475-81-0
D-Glaucine (CAS 475-81-0) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
D-Glaucine
CAS Number
475-81-0
DTXSID
DTXSID8031100
Molecular Formula
C21H25NO4
InChI Key
RUZIUYOSRDWYQF-HNNXBMFYSA-N
Monoisotopic Mass
355.178358
Synonyms
Boldine dimethyl etherBromcholitinEINECS 207-501-5S-(+)-GlaucineGlauventNSC 34396(S)-5,6,6a7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo(de,g)quinoline1,2,9,10-Tetramethoxy-6a-alpha-aporphineUNII-NU19306XA7Glaucine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| NU19306XA7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NU19306XA7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NU19306XA7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =545 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Plant Extract
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
GLAUCINE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
2
Frequently Asked Questions
Is D-Glaucine used in cosmetics?
Yes, D-Glaucine is also indexed as a cosmetic ingredient under the name Glaucine. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for D-Glaucine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is D-Glaucine used outside industrial chemicals?
D-Glaucine also appears in cosmetics, pharmaceutical databases.