What is the NOAEL for Cyclohexaneacetic acid, 2-propenyl ester?
Cyclohexaneacetic acid, 2-propenyl ester has 8 NOAEL studies in the database. The lowest reported value is M6J8835739 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Cyclohexaneacetic acid, 2-propenyl ester
Also known as: 4-09-00-00039, Acetic acid, cyclohexyl-, allyl ester, Allyl cyclohexylacetate, Allyl hexahydrophenylacetate, BRN 2575626 (+6 more)
CAS 4728-82-9
Cyclohexaneacetic acid, 2-propenyl ester (CAS 4728-82-9) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
Cross-Vertical Regulatory Divergence
Cyclohexaneacetic acid, 2-propenyl ester is classified GHS Danger (H301, H311, H302, H312, H315, H319) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Cyclohexaneacetic acid, 2-propenyl ester
CAS Number
4728-82-9
DTXSID
DTXSID9063580
Molecular Formula
C11H18O2
InChI Key
UECFOOSFSUDPOR-UHFFFAOYSA-N
Monoisotopic Mass
182.13068
Synonyms
4-09-00-00039Acetic acid, cyclohexyl-, allyl esterAllyl cyclohexylacetateAllyl hexahydrophenylacetateBRN 2575626Cyclohexylacetic acid allyl esterEINECS 225-230-0FEMA No. 20232-Propenyl cyclohexaneacetate2-Propen-1-yl cyclohexaneacetateUNII-M6J8835739
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| M6J8835739 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M6J8835739 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M6J8835739 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M6J8835739 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =900 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Cyclohexaneacetic acid, 2-propenyl ester?
Cyclohexaneacetic acid, 2-propenyl ester appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Cyclohexaneacetic acid, 2-propenyl ester used in cosmetics?
Yes, Cyclohexaneacetic acid, 2-propenyl ester is also indexed as a cosmetic ingredient under the name Allyl Cyclohexylacetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Cyclohexaneacetic acid, 2-propenyl ester come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Cyclohexaneacetic acid, 2-propenyl ester have different safety status in cosmetics vs industrial chemicals?
Cyclohexaneacetic acid, 2-propenyl ester is classified GHS Danger (H301, H311, H302, H312, H315, H319) in the chemicals database but is restricted in EU cosmetics.
Is Cyclohexaneacetic acid, 2-propenyl ester used outside industrial chemicals?
Cyclohexaneacetic acid, 2-propenyl ester also appears in cosmetics, food safety, cannabis databases.