Also known as: (3S,3'S)-3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione, 3,3'-Dihydroxy-beta,beta-carotene-4,4'-dione, (3S,3'S)-, Astaxanthin, beta,beta-Carotene-4,4'-dione, 3,3'-dihydroxy-, (3S,3'S)-, β,β-Carotene-4,4'-dione, 3,3'-dihydroxy-, (3S,3'S)- (+14 more)
CAS 472-61-7
3,3'-Dihydroxy-beta-carotene-4,4'-dione (CAS 472-61-7) is a chemical substance. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.034 | mg/kg bw | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.034 | mg/kg bw | ADI | - | Consumers | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.2 | mg/kg bw | ADI | - | Consumers - Adults | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =0.2 | mg/kg bw | ADI | - | Consumers - Adults | EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx |
| =3.4 | mg/kg bw/day | BMDL (10) | oral | Rat | ToxValDB_EFSA |
| 8XPW32PR7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8XPW32PR7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8XPW32PR7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8XPW32PR7I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =14 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_EFSA |
| =14 | mg/kg bw/day | NOAEL | oral: unspecified | Mouse | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =14 | mg/kg bw/day | NOAEL | oral: unspecified | Mouse | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
Showing 12 of 12 studies
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS pharmaceutical records from drug and bioactivity sources.
Same-CAS food additive, ADI, and GRAS records where available.
1 food-safety record found.
View full food safety profile →Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →3,3'-Dihydroxy-beta-carotene-4,4'-dione has 12 NOAEL studies in the database. The lowest reported value is 0.034 mg/kg bw in Consumers. Source: EFSA_OpenFoodTox_EFSA_ReferenceValues.xlsx.
3,3'-Dihydroxy-beta-carotene-4,4'-dione appears on 2 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Canada; pharmaceutical. Source: EPA CPDat.
Yes, 3,3'-Dihydroxy-beta-carotene-4,4'-dione is also indexed as a cosmetic ingredient under the name Astaxanthin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
3,3'-Dihydroxy-beta-carotene-4,4'-dione also appears in cosmetics, pharmaceutical, food safety, cannabis databases.