Danger GHS07GHS05 NOAEL Data REACH Registered Cosmetic Ingredient

2-Propenoic acid, 3-(trimethoxysilyl)propyl ester

Also known as: 3-(Trimethoxysilyl)propyl 2-propenoate

CAS 4369-14-6

2-Propenoic acid, 3-(trimethoxysilyl)propyl ester (CAS 4369-14-6) is a chemical substance with GHS signal word Danger; key hazard signal: H332; H314; H317; H412. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, ECHA REACH.

View cosmetic safety profile for ACRYLOYLOXY PROPYLTRIMETHOXYLANE →

SOURCE noael studies public
NOAEL studies
3
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields
Name
2-Propenoic acid, 3-(trimethoxysilyl)propyl ester
CAS Number
4369-14-6
DTXSID
DTXSID6063436
Molecular Formula
C9H18O5Si
InChI Key
KBQVDAIIQCXKPI-UHFFFAOYSA-N
Monoisotopic Mass
234.09235
Synonyms
3-(Trimethoxysilyl)propyl 2-propenoate

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
Acute Tox. 4 *; Skin Corr. 1B; Skin Sens. 1; Aquatic Chronic 3H332; H314; H317; H412GHS07; GHS05Danger

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 20 records
SolventChemical reaction regulatorAdhesion/cohesion promoterWetting agent (non-aqueous)

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 3 of 3 studies
ValueUnitEndpointRouteSpeciesSource
=130mg/m3DNEL systemicinhalationHumanToxValDB_GESTIS_DNEL
=40mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID
>=1000mg/kg bw/dayNOAELoralRatToxValDB_ECHA_IUCLID

Showing 3 of 3 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registeredacrylic acid, 3-(trimethoxysilyl)propyl ester419-560-6ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Solvents
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for 2-Propenoic acid, 3-(trimethoxysilyl)propyl ester?

2-Propenoic acid, 3-(trimethoxysilyl)propyl ester (CAS 4369-14-6) is classified under EU CLP Annex VI as Acute Tox. 4 *; Skin Corr. 1B; Skin Sens. 1; Aquatic Chronic 3 with signal word Danger. Hazard statements: H332; H314; H317; H412. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for 2-Propenoic acid, 3-(trimethoxysilyl)propyl ester?

2-Propenoic acid, 3-(trimethoxysilyl)propyl ester has 3 NOAEL studies in the database. The lowest reported value is 40 mg/kg bw/day via oral in Rat. Source: ToxValDB_ECHA_IUCLID.

Is 2-Propenoic acid, 3-(trimethoxysilyl)propyl ester used in cosmetics?

Yes, 2-Propenoic acid, 3-(trimethoxysilyl)propyl ester is also indexed as a cosmetic ingredient under the name ACRYLOYLOXY PROPYLTRIMETHOXYLANE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 2-Propenoic acid, 3-(trimethoxysilyl)propyl ester come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does 2-Propenoic acid, 3-(trimethoxysilyl)propyl ester have different safety status in cosmetics vs industrial chemicals?

2-Propenoic acid, 3-(trimethoxysilyl)propyl ester is classified GHS Danger (H332, H314, H317, H412) in the chemicals database but is allowed in EU cosmetics.

Is 2-Propenoic acid, 3-(trimethoxysilyl)propyl ester used outside industrial chemicals?

2-Propenoic acid, 3-(trimethoxysilyl)propyl ester also appears in cosmetics databases.