NOAEL Data IARC Group 2A REACH Registered Cosmetic Ingredient

Silicon carbide

Also known as: SiC, Silicon carbide (SiC), Carbolon, Carborundeum, Crystar (+7 more)

CAS 409-21-2

Silicon carbide (CAS 409-21-2) is a chemical substance; key hazard signal: IARC Group 2A. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, IARC, ECHA REACH, ILO ICSC, OSHA.

View cosmetic safety profile for Silicon Carbide →

Cross-Vertical Regulatory Divergence

Silicon carbide is classified GHS Danger (H350i, H372, H350, H370, H225, H315, H319, H335) in the chemicals database but is allowed in EU cosmetics.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields

Name

Silicon carbide

CAS Number

409-21-2

DTXSID

DTXSID5052751

Molecular Formula

CSi

InChI Key

HBMJWWWQQXIZIP-UHFFFAOYSA-N

Monoisotopic Mass

39.976927

Synonyms

SiCSilicon carbide (SiC)CarbolonCarborundeumCrystarEINECS 206-991-8NicalonSC 9UNII-WXQ6E537EWSiliziumkarbid[SiC]silicon(IV) carbide

IARC Carcinogen Classification

Carcinogenic hazard classification from IARC monograph evaluations.

SOURCE IARC Monographs on the Identification of Carcinogenic Hazards to Humans 1 records

Group	Meaning	Evaluated	Volume
Group 2A	Probably carcinogenic	2014	111

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records

Field	Value
Short-term Effects	May cause mechanical irritation.

OSHA Exposure Limits

Occupational exposure limits from OSHA, NIOSH, and ACGIH rows.

SOURCE OSHA / NIOSH / ACGIH occupational exposure limits 4 records

Agency	Metric	Value	ppm	mg/m3	Skin
OSHA	TWA	15 mg/m³ (total dust), 5 mg/m³ (respirable fraction)	-	15	N
NIOSH	TWA	10 mg/m³ (total dust), 5 mg/m³ (resp)	-	10	N
ACGIH	TWA	Nonfibrous: 10 mg/m³ (inhalable particulate matter), 3 mg/m³ (respirable particulate matter) *The values are for particulate matter containing no asbestos and <1% crystalline silica. Fibrous (including whiskers): 0.1 f/cc (respirable fibers), see footnote [F] in the TLV booklet. [2002]	-	10	N
CAL/OSHA	TWA	10 mg/m³ (total dust), 5 mg/m³ (respirable fraction)	-	10	N

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 7 records

AbrasiveProcessing aids not otherwise specifiedFiller

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 3 records

List	Keyword	Source
drinking_water; Europe; manufacturing; plastic_additive	Belgaqua	CPCat
active_ingredient; Australia	Australian Pesticides and Veterinary Medicines Authority	CPCat
SCIL (9/2019)	USEPA	Safer Chemical Ingredients List

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies

Value	Unit	Endpoint	Route	Species	Source
WXQ6E537EW	UNII	FDA UNII substance identifier	-	-	openFDA substances
WXQ6E537EW	UNII	FDA UNII substance identifier	-	-	openFDA substances
WXQ6E537EW	UNII	FDA UNII substance identifier	-	-	openFDA substances
WXQ6E537EW	UNII	FDA UNII substance identifier	-	-	openFDA substances
2A	IARC group	IARC carcinogenicity classification	-	-	IARC Monographs
2	unitless	IARC group	-	-	NTP_ICE_cancer
=2000	mg/kg bw	LD50	oral	Rat	NTP_ICE_acute_oral

Showing 7 of 7 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Silicon carbide	206-991-8	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Frequently Asked Questions

What is the NOAEL for Silicon carbide?

Silicon carbide has 7 NOAEL studies in the database. The lowest reported value is WXQ6E537EW UNII. Source: openFDA substances.

What regulatory lists include Silicon carbide?

Silicon carbide appears on 3 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, active_ingredient; Australia, SCIL (9/2019). Source: EPA CPDat.

Is Silicon carbide a carcinogen according to IARC?

Silicon carbide is classified by IARC as Group 2A — probably carcinogenic to humans (evaluated 2014). Source: IARC Monographs on the Identification of Carcinogenic Hazards to Humans.

What are the occupational exposure limits for Silicon carbide?

Occupational exposure limits for Silicon carbide are set by OSHA, NIOSH, ACGIH. 4 limit values from official agencies are documented in the database. Source: OSHA, NIOSH, ACGIH.

Is Silicon carbide used in cosmetics?

Yes, Silicon carbide is also indexed as a cosmetic ingredient under the name Silicon Carbide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Silicon carbide come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, IARC Monographs, ECHA REACH, ILO/WHO ICSC, OSHA/NIOSH/ACGIH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Silicon carbide have different safety status in cosmetics vs industrial chemicals?

Silicon carbide is classified GHS Danger (H350i, H372, H350, H370, H225, H315, H319, H335) in the chemicals database but is allowed in EU cosmetics.

Is Silicon carbide used outside industrial chemicals?

Silicon carbide also appears in cosmetics databases.