What is the NOAEL for 2-Butyloctan-1-ol?
2-Butyloctan-1-ol has 12 NOAEL studies in the database. The lowest reported value is 0.658 uL/min/10^6 cells in Human. Source: NTP_ICE_adme_parameters.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Butyloctan-1-ol
Also known as: 1-Octanol, 2-butyl-, 2-Butyl-1-octanol, Jarcol I 12, Isofol 12, Guerbet dodecanol (+14 more)
CAS 3913-02-8
2-Butyloctan-1-ol (CAS 3913-02-8) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
12
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
2-Butyloctan-1-ol
CAS Number
3913-02-8
DTXSID
DTXSID0044818
Molecular Formula
C12H26O
InChI Key
XMVBHZBLHNOQON-UHFFFAOYSA-N
Monoisotopic Mass
186.198365
Synonyms
1-Octanol, 2-butyl-2-Butyl-1-octanolJarcol I 12Isofol 12Guerbet dodecanolGuerbet C122-butyloctane-1-ol2-butiloctan-1-ol4-01-00-01855BRN 17385222-ButyloctanolEINECS 223-470-0
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
SolventHumectant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| air; Cons electronics mech appliances and machinery; detected; emissions; Europe | Danish Environmental Protection Agency | Danish EPA |
| detected; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| air; detected; emissions; Europe; Other direct contact consumer goods | Danish Environmental Protection Agency | Danish EPA |
| Arts and crafts/Office supplies - fabric treatment and dye; detected | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 12 of 12 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0.658 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| =123.3 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| N442D9VO79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N442D9VO79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N442D9VO79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| N442D9VO79 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| =13000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =26533 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =37434 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 12 of 12 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2-butyloctan-1-ol | 223-470-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Humectants
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3183262
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2-Butyloctan-1-ol?
2-Butyloctan-1-ol appears on 4 regulatory/inventory lists including air; Cons electronics mech appliances and machinery; detected; emissions; Europe, detected; Europe; Other direct contact consumer goods, air; detected; emissions; Europe; Other direct contact consumer goods, and 1 more. Source: EPA CPDat.
Is 2-Butyloctan-1-ol used in cosmetics?
Yes, 2-Butyloctan-1-ol is also indexed as a cosmetic ingredient under the name Butyloctanol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Butyloctan-1-ol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Butyloctan-1-ol used outside industrial chemicals?
2-Butyloctan-1-ol also appears in cosmetics, pharmaceutical databases.