What is the NOAEL for Minoxidil?
Minoxidil has 6 NOAEL studies in the database. The lowest reported value is 5965120SH1 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Minoxidil
Also known as: 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide, Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide, 2,6-Diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate, 5-25-12-00317, BRN 0886240 (+13 more)
CAS 38304-91-5
Minoxidil (CAS 38304-91-5) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
24 fields
Name
Minoxidil
CAS Number
38304-91-5
DTXSID
DTXSID9040685
Molecular Formula
C9H15N5O
InChI Key
ZFMITUMMTDLWHR-UHFFFAOYSA-N
Monoisotopic Mass
209.12766
Synonyms
2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxidePyrimidine, 2,4-diamino-6-piperidino-, 3-oxide2,6-Diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate5-25-12-00317BRN 08862402,3-Dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamineEINECS 253-874-26-Piperidino-2,4-diaminopyrimidine 3-oxide6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxideRegaine2,6-Diamino-4-piperidinopyrimidin-1-oxidTheroxidil
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Softener and conditionerHair fixative
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 5965120SH1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5965120SH1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5965120SH1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5965120SH1 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
| =1321 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 6 of 6 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
MINOXIDIL
ChEMBL Phase
4
Adverse Events
1252
Bioactivity
5
Frequently Asked Questions
What regulatory lists include Minoxidil?
Minoxidil appears on 3 regulatory/inventory lists including banned; Europe; Personal care, pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Minoxidil used in cosmetics?
Yes, Minoxidil is also indexed as a cosmetic ingredient under the name Minoxidil. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Minoxidil come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Minoxidil used outside industrial chemicals?
Minoxidil also appears in cosmetics, pharmaceutical databases.