NOAEL Data REACH Registered Cosmetic Ingredient

5-Cyclohexadecen-1-one

Also known as: Toray-musk, Globanone, 5-Cyclohexadecenone, EINECS 253-568-9

CAS 37609-25-9

5-Cyclohexadecen-1-one (CAS 37609-25-9) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for 5-Cyclohexadecenone →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 10 fields
Name
5-Cyclohexadecen-1-one
CAS Number
37609-25-9
DTXSID
DTXSID8047139
Molecular Formula
C16H28O
InChI Key
ABRIMXGLNHCLIP-UHFFFAOYSA-N
Monoisotopic Mass
236.214016
Synonyms
Toray-muskGlobanone5-CyclohexadecenoneEINECS 253-568-9

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 13 records
Fragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
IFRA TransparencyIFRAIFRA
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
1DAH7E9E0DUNIIFDA UNII substance identifier--openFDA substances
1DAH7E9E0DUNIIFDA UNII substance identifier--openFDA substances
1DAH7E9E0DUNIIFDA UNII substance identifier--openFDA substances
1DAH7E9E0DUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
4unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 6 of 6 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered5-cyclohexadecen-1-one253-568-9ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for 5-Cyclohexadecen-1-one?

5-Cyclohexadecen-1-one has 6 NOAEL studies in the database. The lowest reported value is 1DAH7E9E0D UNII. Source: openFDA substances.

What regulatory lists include 5-Cyclohexadecen-1-one?

5-Cyclohexadecen-1-one appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.

Is 5-Cyclohexadecen-1-one used in cosmetics?

Yes, 5-Cyclohexadecen-1-one is also indexed as a cosmetic ingredient under the name 5-Cyclohexadecenone. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 5-Cyclohexadecen-1-one come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 5-Cyclohexadecen-1-one used outside industrial chemicals?

5-Cyclohexadecen-1-one also appears in cosmetics databases.