NOAEL Data Cosmetic Ingredient

Rosamox

Also known as: 4a(2H)​-​Phenanthrenecarboxyl​ic acid, 1,​3,​4,​9,​10,​10a-​hexahydro-​5,​6-​dihydroxy-​1,​1-​dimethyl-​7-​(1-​methylethyl)​-​, (4aR,​10aS)​-, 4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-trans)-, Podocarpa-8,11,13-trien-17-oic acid, 11,12-dihydroxy-13-isopropyl-, (4aR,10aS)-1,3,4,9,10,10a-Hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-4a(2H)-phenanthrenecarboxylic acid, (+)-Carnosic acid (+3 more)

CAS 3650-09-7

Rosamox (CAS 3650-09-7) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Carnosic Acid →

SOURCE noael studies public
NOAEL studies
6
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields
Name
Rosamox
CAS Number
3650-09-7
DTXSID
DTXSID20904450
Molecular Formula
C20H28O4
InChI Key
QRYRORQUOLYVBU-VBKZILBWSA-N
Monoisotopic Mass
332.198759
Synonyms
4a(2H)​-​Phenanthrenecarboxyl​ic acid, 1,​3,​4,​9,​10,​10a-​hexahydro-​5,​6-​dihydroxy-​1,​1-​dimethyl-​7-​(1-​methylethyl)​-​, (4aR,​10aS)​-4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-trans)-Podocarpa-8,11,13-trien-17-oic acid, 11,12-dihydroxy-13-isopropyl-(4aR,10aS)-1,3,4,9,10,10a-Hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-4a(2H)-phenanthrenecarboxylic acid(+)-Carnosic acidCarnosic acidRoseOxSalvin

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Antioxidant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 6 of 6 studies
ValueUnitEndpointRouteSpeciesSource
LI791SXT24UNIIFDA UNII substance identifier--openFDA substances
LI791SXT24UNIIFDA UNII substance identifier--openFDA substances
LI791SXT24UNIIFDA UNII substance identifier--openFDA substances
LI791SXT24UNIIFDA UNII substance identifier--openFDA substances
=563mg/kg bw/dayNOAELoral: gavageRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
=563mg/kg bw/dayNOAELoral: gavageRatEFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

Showing 6 of 6 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Preservative
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CARNOSIC ACID
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
8
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

1 food-safety record found.

View full food safety profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Rosamox?

Rosamox has 6 NOAEL studies in the database. The lowest reported value is LI791SXT24 UNII. Source: openFDA substances.

Is Rosamox used in cosmetics?

Yes, Rosamox is also indexed as a cosmetic ingredient under the name Carnosic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Rosamox come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is Rosamox used outside industrial chemicals?

Rosamox also appears in cosmetics, pharmaceutical, food safety, cannabis databases.