What is the NOAEL for Dl-Neomenthol?
Dl-Neomenthol has 6 NOAEL studies in the database. The lowest reported value is 10 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Dl-Neomenthol
Also known as: Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2R,5S)-rel-, Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1α,2α,5β)-(±)-, Menthol, trans-1,3,trans-1,4-(±)-, rel-(1R,2R,5S)-5-Methyl-2-(1-methylethyl)cyclohexanol, (+/-)-Neomenthol (+5 more)
CAS 3623-51-6
Dl-Neomenthol (CAS 3623-51-6) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Dl-Neomenthol is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Dl-Neomenthol
CAS Number
3623-51-6
DTXSID
DTXSID20883998
Molecular Formula
C10H20O
InChI Key
NOOLISFMXDJSKH-UTLUCORTSA-N
Monoisotopic Mass
156.151415
Synonyms
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2R,5S)-rel-Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1α,2α,5β)-(±)-Menthol, trans-1,3,trans-1,4-(±)-rel-(1R,2R,5S)-5-Methyl-2-(1-methylethyl)cyclohexanol(+/-)-NeomentholCyclohexanol, 5-methyl-2-(1-methylethyl)-, (1α,2α,5β)-neo-MentholCYCLOHEXANOL, 5-METHYL-2-(ISOPROPYL)-, (1α ,2α,5β)-(+-)-EINECS No.: 222-824-1Neomenthol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =10 | mg/m3 | DNEL local | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =66.1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 89S3KO7RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 89S3KO7RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 89S3KO7RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 89S3KO7RR9 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (±)-neomenthol | 222-824-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include Dl-Neomenthol?
Dl-Neomenthol appears on 2 regulatory/inventory lists including IFRA Transparency, consumer_product. Source: EPA CPDat.
Is Dl-Neomenthol used in cosmetics?
Yes, Dl-Neomenthol is also indexed as a cosmetic ingredient under the name NEOMENTHOL. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dl-Neomenthol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does Dl-Neomenthol have different safety status in cosmetics vs industrial chemicals?
Dl-Neomenthol is classified GHS Danger (H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Dl-Neomenthol used outside industrial chemicals?
Dl-Neomenthol also appears in cosmetics databases.