What is the NOAEL for Tetrahydrocurcumin?
Tetrahydrocurcumin has 6 NOAEL studies in the database. The lowest reported value is 173 uL/min/10^6 cells in Human. Source: NTP_ICE_adme_parameters.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Tetrahydrocurcumin
Also known as: Tetrahydrodiferuloylmethane, 3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione, 1,7-Bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione, AS-KTC 004 (+5 more)
CAS 36062-04-1
Tetrahydrocurcumin (CAS 36062-04-1) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Tetrahydrocurcumin
CAS Number
36062-04-1
DTXSID
DTXSID30865801
Molecular Formula
C21H24O6
InChI Key
LBTVHXHERHESKG-UHFFFAOYSA-N
Monoisotopic Mass
372.157288
Synonyms
Tetrahydrodiferuloylmethane3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedione1,7-Bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dioneAS-KTC 004HZIV 81-2NSC 687845SabiwhiteUNII-00U0645U03QA-0342
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Antioxidant
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 173 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| 00U0645U03 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 00U0645U03 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 00U0645U03 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 00U0645U03 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 0.0501 | fraction | Fu | - | Human | NTP_ICE_adme_parameters |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3,5-Heptamedopme. 1,7-bis(hydroxy-3methoxyphenyl)heptane | 609-201-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed_with_terms
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
TETRAHYDROCURCUMIN
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
3
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
Is Tetrahydrocurcumin used in cosmetics?
Yes, Tetrahydrocurcumin is also indexed as a cosmetic ingredient under the name TETRAHYDROCURCUMIN. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Tetrahydrocurcumin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Tetrahydrocurcumin used outside industrial chemicals?
Tetrahydrocurcumin also appears in cosmetics, pharmaceutical, cannabis databases.