What is the NOAEL for Hexadecyl dihydrogen phosphate?
Hexadecyl dihydrogen phosphate has 4 NOAEL studies in the database. The lowest reported value is VT07D6X67O UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Hexadecyl dihydrogen phosphate
Also known as: EINECS 222-581-1, UNII-VT07D6X67O
CAS 3539-43-3
Hexadecyl dihydrogen phosphate (CAS 3539-43-3) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Hexadecyl dihydrogen phosphate is classified GHS Danger (H315, H318) in the chemicals database but is allowed in EU cosmetics at max 6%.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
8 fields
Name
Hexadecyl dihydrogen phosphate
CAS Number
3539-43-3
DTXSID
DTXSID1045039
Molecular Formula
C16H35O4P
InChI Key
ZUVCYFMOHFTGDM-UHFFFAOYSA-N
Monoisotopic Mass
322.227297
Synonyms
EINECS 222-581-1UNII-VT07D6X67O
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
2 records
Surfactant (surface active agent)Emulsifier
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| VT07D6X67O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VT07D6X67O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VT07D6X67O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VT07D6X67O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Hexadecyl dihydrogen phosphate | 222-581-1 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
6%
Category
sunscreen
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
HEXADECYL DIHYDROGEN PHOSPHATE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Frequently Asked Questions
What regulatory lists include Hexadecyl dihydrogen phosphate?
Hexadecyl dihydrogen phosphate appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Hexadecyl dihydrogen phosphate used in cosmetics?
Yes, Hexadecyl dihydrogen phosphate is also indexed as a cosmetic ingredient under the name Cetyl Phosphate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hexadecyl dihydrogen phosphate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Hexadecyl dihydrogen phosphate have different safety status in cosmetics vs industrial chemicals?
Hexadecyl dihydrogen phosphate is classified GHS Danger (H315, H318) in the chemicals database but is allowed in EU cosmetics at max 6%.
Is Hexadecyl dihydrogen phosphate used outside industrial chemicals?
Hexadecyl dihydrogen phosphate also appears in cosmetics, pharmaceutical databases.