What is the NOAEL for Sodium ethylparaben?
Sodium ethylparaben has 9 NOAEL studies in the database. The lowest reported value is 10 mg/kg bw/day in Consumers. Source: EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Sodium ethylparaben
Also known as: EINECS 252-487-6, Ethyl p-hydroxybenzoate, sodium salt, UNII-Z0D00IVA10
CAS 35285-68-8
Sodium ethylparaben (CAS 35285-68-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Sodium ethylparaben is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics at max 0.4%.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
9
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
8 fields
Name
Sodium ethylparaben
CAS Number
35285-68-8
DTXSID
DTXSID0042402
Molecular Formula
C9H10O3.Na
InChI Key
QYNMSPKSYXPZHG-UHFFFAOYSA-M
Synonyms
EINECS 252-487-6Ethyl p-hydroxybenzoate, sodium saltUNII-Z0D00IVA10
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Preservative
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 9 of 9 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=10 | mg/kg bw/day | ADI (group) | - | Consumers | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
| Z0D00IVA10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z0D00IVA10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z0D00IVA10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| Z0D00IVA10 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1030 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
| =1030 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
| =1043 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
| =1043 | mg/kg bw/day | NOAEL | - | Rat | EFSA_OpenFoodTox_OpenFoodToxTX22809_2023.xlsx |
Showing 9 of 9 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Sodium 4-ethoxycarbonylphenoxide | 252-487-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
0.4%
Category
Preservative
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
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EFSA / FDA GRAS
1 records
E215 — ADI: 10 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Sodium ethylparaben?
Sodium ethylparaben appears on 2 regulatory/inventory lists including active_ingredient; Europe; Pesticides, inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Sodium ethylparaben used in cosmetics?
Yes, Sodium ethylparaben is also indexed as a cosmetic ingredient under the name Sodium Ethylparaben. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sodium ethylparaben come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Sodium ethylparaben have different safety status in cosmetics vs industrial chemicals?
Sodium ethylparaben is classified GHS Danger (H318, H319) in the chemicals database but is allowed in EU cosmetics at max 0.4%.
Is Sodium ethylparaben used outside industrial chemicals?
Sodium ethylparaben also appears in cosmetics, food safety, cannabis databases.